U.S.-traded shares of Teva Pharmaceutical Industries Ltd rose 3 percent to $58.53 a day after the world's largest generic drugmaker set a 2015 revenue target of $31 billion, more than double its current annual amount.
Teva forecast major growth in overall use of generics.
The Dow Jones industrial average <.DJI> dropped 25.47 points, or 0.24 percent, to 10,581.39. The Standard & Poor's 500 Index <.SPX> fell 1.14 points, or 0.10 percent, to 1,140.55. The Nasdaq Composite Index <.IXIC> gained 6.95 points, or 0.30 percent, to 2,307.00.
Wall Street fell at the open after data showed an unexpected decline in U.S. non-farm payrolls in December.
(Editing by Padraic Cassidy)