Real Madrid have been dealt a blow heading into the final weeks of the season with the news that Cristiano Ronaldo has suffered a hamstring injury that looks highly likely to keep him out of next Wednesday’s Copa del Rey final against Barcelona and potentially beyond.

Ronaldo missed both the clash with Real Sociedad on Saturday with a knee problem suffered in the first leg of Madrid’s Champions League quarterfinal with Borussia Dortmund last week. He then attempted to take part in the return leg in Dortmund but could only last five minutes of the team’s training session on Monday. Despite suffering the injury, he was still named among the substitutes on Tuesday, although was not called upon.

“Medical tests performed on Cristiano Ronaldo have revealed an injury to the player's left biceps femoris muscle,” a statement on the Real Madrid website read. “Pending a medical evaluation.”

The statement did not specify the severity of the injury or the length of time he could miss. Still, it is extremely difficult to imagine a player returning from a muscular injury in just a week. That would mean Ronaldo missing out on Madrid’s first opportunity to claim silverware this season against fierce rivals Barcelona in the Copa del Rey final.

Madrid-based sports daily AS believes that the injury could be a small tear to the hamstring, which could keep him out for 15 days. That would also make Ronaldo extremely doubtful for the first leg of a Champions League semifinal against as yet unknown opponents either on April 22 or the following day.

The loss of a player who has scored an incredible 45 goals in all competitions this season for Madrid will be a major blow to Carlo Ancelotti. However, the club spent a record fee on Gareth Bale last summer to give them another player of similar game-changing attributes. Bale scored his 18th goal of the season in a 4-0 win at Real Sociedad in Ronaldo’s absence, yet Madrid were poor in suffering a 2-0 defeat at Borussia Dortmund and only narrowly scraped through thanks to a 3-0 win in the first leg and a string of missed chances by the Bundesliga side.

Real Madrid will discover the identity of their opponents in the last four when the draw is made on Friday.