The Denver Broncos meet the Seattle Seahawks at Mile High Stadium at 9pm EST.
You can watch all the preseason action here.
Peyton Manning will enter Mile High for the first time as the Broncos starting quarterback Saturday. He will play the entire first half, after taking just a dozen snaps in Denver's 31-3 preseason win at Chicago. Most of the Bronco's starters will play only the first half like Manning.
Tim Tebow was the last quarterback to rock Mile High when Denver defeated the Pittsburgh Steelers in the AFC Wild Card round in 2011. Manning will look to improve a Broncos passing game that managed only 152.1 per game, good for 31st in NFL last season.
Those to benefit most from Manning's veteran touch could be tight ends Joel Dreessen and Jacob Tamme. Manning has always had an affinity for working his tight ends into every play he calls.
Tamme joins the Broncos from Manning's old squad the Indianapolis Colts and has valuable experience with the playmaker. Manning's last season in the NFL was 2010, and Tamme earned 67 receptions and 631 yards that year.
Dreesen signed with the Broncos in the offseason after five seasons with the Houston Texans and caught 28 balls for 353 yards and six touchdowns in 16 games in 2011. He's proven very durable, as Dreesen has not missed a game since 2007.
Seattle's quarterback situation isn't quite as sewn up as they come off a 27-17 victory over the Tennessee Titans. The Seahawks signed Matt Flynn to a long-term deal in the offseason, but he still has to compete with rookie third-round pick Russell Wilson and 2011 starter Tavaris Jackson. The competition may have dwindled down to Flynn and Wilson, as speculation has Seattle trying to trade Jackson.
Flynn will start tonight against the Broncos, and Wilson could play the whole second half, especially if he can repeat his performance of 12-16 and 124 yards against Tennessee.
Seattle's defense will have a huge test against Manning even if it is only the preseason. Rookie defensive end Bruce Irvin did not wow coaches against Tennessee, but has a chance to prove himself if he can get to Manning.
Prediction: All eyes are on Manning to play his first full half of football in a year and a half. Seattle's pass rush looked strong against Tennessee, so after Manning exits Seattle could dominate the rest of the game.
Predicted Score: Seattle 30 Denver 24