Comedian George Lopez will host the final episode of "Lopez Tonight" show on Thursday, a day after TBS announced the show was being dropped after two seasons on the air for poor ratings.

On Wednesday's show, George opened to wild cheering and asked his audience to "settle down, we only have till tomorrow night." He added, "We're not saying goodbye. We're saying -- cable doesn't work."

He also made reference to Charlie Sheen's exit from "Two and a Half Men." 

"People ask me, what are you going to do? Like every TV star before me, I'm gonna find some crack. I'm gonna get on the pipe, lose that unwanted 110 pounds I've been trying to lose. ... I'm straight. I'm fine. My goddesses are a wreck. ... They left me."

Lopez continued, saying he's grateful Sony has decided to make a sequel to The Smurfs, in which he does the voice of Grouchy. "So today I lost some work because I'm brown, but also I got some work because I'm blue."

Conan O'Brien, who bumped Lopez to a later time slot after his debut to TBS, was solemn when he broke the news on his show. "Had it not been for George being so incredibly supportive of me I would not have come to TBS," Conan said. "... Tonight all of our thoughts are with George and his staff and crew."

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