Matt Barkley Chicago Bears
Matt Barkley threw for 362 yards against the Green Bay Packers at Soldier Field on Dec. 18, 2016 in Chicago, and he could help the Chicago Bears upset the Washington Redskins in Week 16. Getty Images

With most of the playoff spots still up for grabs, many of the games in Week 16 of the 2016 NFL season are expected to be close. Only one team is favored by double-digits, and all but two of the games on the schedule feature a betting line of seven points or fewer.

Favorites had a slight edge on the underdogs in Week 15, going 8-7-1 against the spread. Five road teams are favored in Week 16, all of whom have winning records.

Below are picks against the spread for every game in Week 16, as well as updated betting odds at Las Vegas and online sportsbooks. Betting lines and trends are courtesy of OddsShark.

New York Giants (-2.5) at Philadelphia Eagles

The Giants are the easy pick Thursday night. With eight wins in their last nine games, New York is still vying for a top playoff seed. The Eagles have lost seven of their last eight contests with nothing to play for. Carson Wentz has the NFL’s second-worst passer rating since Week 6, and he’ll struggle against a defense that’s allowed the second-worst passer rating all season.

Prediction ATS: New York

Washington Redskins (-3.5) at Chicago Bears

With Matt Barkley at quarterback, the Bears have been in just about every game. Since beating the 49ers, they’ve lost by a field goal to both the Lions and Packers, and Chicago hasn't been beaten by more than one score since Week 10. Washington has given up fewer than 20 points in just one game this year, and Saturday’s contest should be a high-scoring affair that comes down to the wire.

Prediction ATS: Chicago

Miami Dolphins (+3.5) at Buffalo Bills

Miami defeated Buffalo by a field goal earlier this year, but that was with Ryan Tannehill under center. Matt Moore should come back to earth following his four-touchdown performance against the Jets, and the Bills’ running game could keep them in the wild card hunt. The Dolphins are 2-9 against the spread in their last 11 road games against the Bills.

Prediction ATS: Buffalo

Tampa Bay Buccaneers (+3) at New Orleans Saints

The betting line indicates that the Bucs and Saints are even on a neutral field, but that simply hasn’t been the case for almost an entire season. New Orleans’ offense has been too inconsistent, and it could come back down to earth after scoring 48 points in Week 15. The Saints scored just 11 points in Tampa Bay two weeks ago, and they are averaging only 19 points per game in five contests against top-10 scoring defenses. Prior to their Week 15 loss in Dallas, Tampa Bay had given up an average of 12.8 points in their five-game winning streak.

Prediction ATS: Tampa Bay

Atlanta Falcons (-2.5) at Carolina Panthers

The Falcons have quietly put together one of the best offensive seasons in NFL history. Scoring a league-high 33.5 points per game, Matt Ryan and Co. might not have trouble getting into the end zone against Carolina’s No.22 ranked defense. The Panthers haven’t had any sustained success this season, and they seem due for a loss after two straight wins.

Prediction ATS: Atlanta

Minnesota Vikings (+6.5) at Green Bay Packers

The Vikings and Packers are headed in two different directions. Minnesota has just two wins since Week 5, and only the Rams rank worse in total offense in 2016. Aaron Rodgers is back to looking like the NFL’s top quarterback, and the Vikings have little chance to keep pace with the Packers. Minnesota is 2-5 against the spread in their last seven games at Lambeau Field.

Prediction ATS: Green Bay

New York Jets (+16.5) at New England Patriots

There is a major disparity between the NFL’s elite and the league’s worst teams, and few teams are further apart than the Patriots and Jets. All three teams that were favored by double-digits covered the spread in Week 15 and that trend should continue Saturday. New England didn’t lose against the spread when favored by at least 13 points in the last five weeks. Other than their victory against the one-win 49ers, Bryce Petty and the Jets have lost twice in the past three weeks by 31 points.

Prediction ATS: New England

Tennessee Titans (-5) at Jacksonville Jaguars

The Jaguars haven’t won since Week 6, and only two of their defeats during their nine-game losing streak have come by less than five points. The Titans are probably the best team in the AFC South, having defeated the likes of Green Bay, Denver and Kansas CIty (all of whom beat Jacksonville.) Marcus Mariota had a 148.1 passer rating in the first meeting between these two teams, and the quarterback should be in for another big day, less than a week after the firing of Jaguars’ head coach Gus Bradley.

Prediction ATS: Tennessee

San Diego Chargers (-6) at Cleveland Browns

The Browns stopped being competitive two months ago, and it’s hard to pick Cleveland when they are getting fewer than seven points. Cleveland has allowed at least 23 points in every game, and it should be the cure for San Diego’s recent offensive woes. Having scored 13 points or fewer in each of the last six weeks, it’d be a surprise if the Browns don’t end the season at 0-16.

Prediction ATS: San Diego

Indianapolis Colts (+3.5) at Oakland Raiders

Andrew Luck has bounced back from a poor season to once again look like a top NFL quarterback. He’s helped the Colts average 35 points in their last four road games, and Indianapolis should be able to move the ball against the NFL’s 25th ranked pass defense. The Raiders have been on the right side of a lot of close games, and it wouldn’t be surprising to see their luck run out Saturday.

Prediction ATS: Indianapolis

San Francisco 49ers (+3.5) at Los Angeles Rams

The 49ers have the NFL’s worst defense, but the Rams can’t seem to move the ball, no matter whom they play. Los Angeles was shut out by San Francisco in the season opener, and the Ram’s offense might not be much better this time around, considering Jared Goff has the league’s worst passer rating.

Prediction ATS: San Francisco

Arizona Cardinals (+8) at Seattle Seahawks

The Seahawks have suffered a few disappointing losses in 2016, but they are simply a different team at home. Seattle is undefeated at CenturyLink Field, defeating their opponents by an average of 13.4 points. Carson Palmer has struggled against good defenses this year, and he might be picked off a few time in a Seattle victory. The Cardinals are 1-4 against the spread in their last five games against the Seahawks, and the game means much more to Seattle, who is trying to secure a first-round playoff bye.

Prediction ATS: Seattle

Cincinnati Bengals (+1.5) at Houston Texans

Brock Osweiler is the worst quarterback that’s started every week in 2016, and Houston’s offense should be better now that he’s been replaced by Tom Savage. The Texans continue to take care of business at home, going 5-1 at NRG Stadium. Cincinnati is 0-10-1 in their last 11 games against winning teams, and they should lose a defensive battle on Christmas Eve night.

Prediction ATS: Houston

Baltimore Ravens (+5) at Pittsburgh Steelers

The Ravens usually play the Steelers close, and if they lose it will probably be by no more than a field goal. Baltimore has won four games in a row against Pittsburgh, including a 21-14 victory in Week 9. The Steelers’ offense hasn’t played up to its potential, failing to reach the 30-point mark in each of the last five games. The Ravens enter Week 16 with the NFL’s fifth-ranked defense.

Prediction ATS: Baltimore

Denver Broncos (+3.5) at Kansas City Chiefs

Kansas City is no place for a struggling offense to fix itself, but that’s exactly what Denver will try to do on Christmas Day. The Chiefs are allowing just 16.6 points per game at home, and the Broncos have totaled one touchdown in the last two weeks.

Prediction ATS: Kansas City

Detroit Lions (+7) at Dallas Cowboys

The Giants seem to be the only team that the Cowboys have trouble with. Dallas is 12-0 against the rest of the league, and Detroit is just 1-3 against teams with winning records.

Prediction ATS: Dallas

Season Record: 116-100-7