There are several interesting games on the Week 17 schedule. Plenty of teams are looking to make the playoffs or improve their seeding, while most of the NFL has nothing to play for, making for some interesting betting lines.

Week 17 could feature several one-sided affairs. Five teams are favored by at least nine points, according to Underdogs were very successful in Week 16, as seven favorites lost straight up.

Below are picks against the spread for every game in Week 17, as well as updated betting odds at Las Vegas casinos.

New York Jets (-3) at Buffalo Bills

Head coach Rex Ryan would like to beat his former team for a second time this year, but the game means nothing for the Bills. A win puts the Jets in the playoffs, and New York is playing terrific football, having won five in a row.

Prediction ATS:  New York

Tampa Bay Buccaneers (+10.5) at Carolina Panthers

Carolina still needs a win to clinch home-field advantage throughout the NFC playoffs, and they shouldn’t have trouble getting it against a team that has lost three of four games against teams with losing records. According to OddsShark, the Panthers are 4-1 against the spread in their last five meetings with Tampa Bay.

Prediction ATS: Carolina

New England Patriots (-10.5) at Miami Dolphins

The Patriots beat the Dolphins by 29 points in their first meeting of the year, and Sunday could be another blowout since Miami’s season is over. New England is still looking to clinch the No.1 seed in the AFC.

Prediction ATS: New England

Baltimore Ravens (+9) at Cincinnati Bengals

The Ravens showed some fight against the Steelers in their upset victory last week, and they could keep things close with the Bengals in Week 17. AJ McCarron has done a serviceable job in place of Andy Dalton, but he hasn’t shown the ability to put up big numbers and help Cincinnati win in blowout fashion.

Prediction ATS: Baltimore

New Orleans Saints (+4) at Atlanta Falcons

Drew Brees has been on fire of late, averaging 355 passing yards in his last three games. He’ll put up more big numbers in a high-scoring affair that could be decided by a field goal.

Prediction ATS: New Orleans

Jacksonville Jaguars (+6) at Houston Texans

Houston has had a lot of success against a weak AFC South this year, going 4-0 against the spread in their last four games against divisional opponents. They should be able to handle Jacksonville as they try to clinch a postseason berth.

Prediction ATS: Houston

Pittsburgh Steelers (-10) at Cleveland Browns

Pittsburgh won’t be upset by one of the NFL’s worst teams for a second straight week. The Steelers should have no problem bouncing back against the team that has one victory since Week 6.

Prediction ATS: Pittsburgh

Oakland Raiders (+6.5) at Kansas CIty Chiefs

There’s little reason to think the Chiefs won’t end the regular season with a 10th straight win. Oakland continues to play hard down the stretch, but Kansas City is the smart pick with the betting line at less than a touchdown.

Prediction ATS: Kansas City

Washington Redskins (+3.5) at Dallas Cowboys

The Cowboys are favored because the Redskins are expected to rest most of their starters, but Dallas’ starting quarterback probably shouldn’t even be in the NFL. With Kellen Moore at quarterback, the Cowboys can’t move the ball, and they could lose another meaningless game.

Prediction ATS: Washington

Detroit Lions (+1) at Chicago Bears

Detroit’s hot play is "too little, too late" for a playoff run, but it can help the Lions finish with seven wins on the year. The Lions have won five of their last seven, and they should end the year on a high note.

Prediction ATS: Detroit

Philadelphia Eagles (+3) at New York Giants

Much like the Dolphins and Titans earlier this season, the Eagles could be rejuvenated following the firing of their head coach. The Giants looked lifeless last week, and they might not put up much of a fight as their season comes to a close.

Prediction ATS: Philadelphia

Minnesota Vikings (+3) at Green Bay Packers

The Packers dominated the Vikings in their first meeting of the season. Sunday’s matchup should be closer, but Green Bay will win again if they force Teddy Bridgewater to make big plays.

Prediction ATS: Green Bay

San Diego Chargers (+9) at Denver Broncos

Brock Osweiler has Denver still in contention for the AFC’s No.1 seed, but the Broncos haven’t been blowing out opponents. In the last 10 meetings between Denver and San Diego, the visiting team is 9-1 against the spread.

Prediction ATS: San Diego

St. Louis Rams (-3.5) at San Francisco 49ers

The Rams seem determined to get to .500, and it looks like they’ll get there the way they’ve been playing of late. The 49ers have nothing to play for, and they’ve lost three consecutive games by double-digits.

Prediction ATS: St. Louis 

Seattle Seahawks (+6.5) at Arizona Cardinals

The Cardinals might be the best team in football, and they should beat the Seahawks after winning in Seattle earlier this season.

Prediction ATS: Arizona

Tennessee Titans (N/A) at Indianapolis Colts

There is no betting line for this contest. IB Times will make an official prediction once a point spread becomes available.

Season Record: 121-112-7