Syracuse swingman Michael Carter-Williams scored 25 points, as No. 4 seed Syracuse upset No. 1 Indiana in Washington, D.C. on Thursday night, 61-50.

In their lowest scoring output of the season, Indiana failed to generate much offense against an effective Syracuse defense that forced 19 turnovers. Tom Crean's squad shot just 33.3 percent from the field, and 62.5 percent from the free-throw line.

Syracuse also blocked 10 shots to go along with 12 steals. 

"Our perimeter defense was tremendous," said Syracuse head coach Jim Boeheim. "This is one of our best defensive teams ever. They play it well."

Carter-Williams was the main spark on offense for Syracuse. The sophomore converted nine of his 19 shots, and only turned the ball over once in 38 minutes.

It was an overall strong effort from the Syracuse backcourt. Brandon Triche added 14 points for Syracuse on six-of-12 shooting.

Syracuse will meet No.3 Marquette, who defeated No. 2 Miami, 71-61. The Golden Eagles advanced to the Elite Eight of the East Region behind excellent shooting. Jamil Wilson, Vander Blue, and Davante Gardner combined to shoot 17-28 from the field for 44 points.

In the West, Ohio State held off Arizona, 73-70. The Buckeyes will face Wichita State, who defeated La Salle, 72-58.