The Yankees advanced to the American League Championship Series with the victory, and will face the Detriot Tigers.
Sabathia cruised for seven innings before experiencing some trouble in the eight inning. The Orioles singled three times and received a walk from Manny Machado to put up their only run.
The Yankees got a solo shot from Curtis Granderson in the seventh inning for some breathing room, and New York was able to post two runs off starter Jason Hammel.
New York only got five hits in the game, and three walks. Eric Chavez, who replaced Alex Rodriguez at third base, failed to reach base in the game, and struck out twice.
It was a difficult loss for the Orioles, who were considered a Cinderella story in the 2012 season. In recent years, the Orioles have struggled behind not only the Yankees but the Boston Red Sox and the Tampa Bay Rays in the talent-rich American League East.
The Yankees host the Tigers on Saturday night at 8 p.m. eastern time.