Stock index futures pointed to a mixed open on Wall Street on Tuesday, with futures for the S&P 500 down 0.02 percent, Dow Jones futures up 0.11 percent and Nasdaq 100 futures down 0.7 percent at 3:45 a.m. EST.
* Apple shares will be in the spotlight after the company said Chief Executive Steve Jobs was taking medical leave for the third time since 2004, reviving fears over the long-term future of the iPhone- and iPad-maker and sending the company's stock traded in Frankfurt tumbling more than 8 percent.
* On the earnings front, investors were bracing for results from a number of companies including Apple, Citigroup
* Goldman Sachs
* Brewing giant SABMiller
* European planemaker Airbus
* South African retailer Massmart's
* European stocks were up 0.7 percent in morning trade, led by mining shares after Rio Tinto's
* The S&P 500 ended a seventh straight week of gains with a banks-led rally amid healthy volume after encouraging financial results from JPMorgan.
* The Dow Jones industrial average <.DJI> added 55.48 points, or 0.47 percent, to 11,787.38. The Standard & Poor's 500 <.SPX> rose 9.48 points, or 0.74 percent, to 1,293.24. The Nasdaq Composite <.IXIC> gained 20.01 points, or 0.73 percent, to 2,755.30.
(Reporting by Blaise Robinson; Editing by Jon Loades-Carter)