Sandra Oh will be saying goodbye to Christina Yan, the character she played on ABC’s hit “Grey’s Anatomy,” as she exits the show after the show’s 10th season. Oh has been a staple on the show since it began in 2005 but will apparently be checking out for good, according to Eonline.com.

"It's been a great privilege to play the character of Cristina Yang on GA and I am both sad and excited to see where this, her final season will take her," Oh said in a statement that was quoted by the entertainment site.

"It was an emotional and deeply creative decision for me and I feel fully supported by Shonda [Rhimes] and the writers. It's so rare in an actor's life to be able to explore and grow a character so fully, so completely. I am profoundly grateful to everyone at GA for the opportunity. I'm excited to celebrate and cherish every moment of my final season on GA with the fans who have made it all possible."

At the moment, no details have been given for how Christina’s departure from "Grey’s Anatomy" will go down, but according to Shondra Rhimes, who is the creator, head writer, and executive producer of the medical drama, Oh’s departure will be worthwhile.

"One of the best days of my life as a writer happened the day Sandra Oh walked in my door to audition and forever changed the course of 'Grey's Anatomy' with her brilliant, nuanced portrayal of Cristina Yang," Rhimes said, according to Eonline.com.

"Over the past 10 seasons, I have been made better by Sandra's trust, faith and friendship and I can't quantify how grateful I am for her collaboration on a character we both love so deeply. This year is going to be bittersweet for us — we're both going to savor every moment of Cristina Yang and then we're going to give her the exit she deserves. And when Sandra walks out of my door, 'Grey's Anatomy' will be once again be forever changed."

Just because Oh is leaving doesn’t mean any other fan favorites like Patrick Dempsey and Ellen Pompeo will be going anywhere soon, at least as far as ABC is concerned. The network said in a statement, “It's our intention to have Grey's on the air for many years to come, with as many of the original cast as possible.”

Check out some of the tweets GA fans shared on Twitter: