Where to watch: Tuesday's play at the All England Club gets underway at 7 a.m. ET. Coverage will be on ESPN2 from 7 a.m. and on ESPN starting at 8 a.m., with a live stream available on ESPN3. Viewers in the U.K. can catch the action across the BBC, with a live stream accessible on the BBC Sport website.
Preview: After rain fell for much of the day on Manic Monday, fans will receive a bonus on Tuesday with four men's round-of-16 matches still to be completed. Juan Martin Del Potro and David Ferrer get the action underway on Centre Court with their eagerly awaited contest.
The victor will have to do without the customary day off before taking on the winner of the match between Andy Murray and Marin Cilic in the quarterfinals. Murray had the upper-hand before the rain intervened, leading by a set and a break.
Mardy Fish will also be hopeful of capitalizing on his advantage as he resumes a set to the good against fifth seed Jo-Wilfried Tsonga.
But the second Tuesday is primarily women's quarterfinal day. After the elimination of Maria Sharapova on Monday there are just two previous Wimbledon winners left in the draw and that is sure to become one by the semifinal stage. In arguably the pick of Tuesday's matches, the winners at SW19 for the past two years, Serena Williams and Petra Kvitova, face off on Centre Court.
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The pair last met in the semifinals in 2010 when Williams, as she did in their only other encounter, came out on top in straight sets. Williams will be relieved to have made it this far after having been pushed the full distance against Yaroslava Shvedova as she was in her previous round with Zheng Jie. Kvitova was also tested in round four, though, as she recovered from a set down to oust Francesca Schiavone.
In an all-German quarterfinal, Sharapova's conqueror Sabine Lisicki looks to continue her second-straight deep run at Wimbledon against Angelique Kerber. After the biggest win of her career, Lisicki will have to ensure that she is up for the match both emotionally and physically.
She will have her work cut out too. Eighth seed Kerber has had a stunning year to date and has also won all four previous meetings against her younger opponent.
With Sharapova now out, there is guaranteed to be a new world No.1 by tournament's end. The woman now favored to assume that honor is second seed Victoria Azarenka. After claiming the Australian Open title earlier this year, the Belarusian continues her quest for a first Wimbledon crown against Tamira Paszek. The Austrian, in her second straight quarterfinal at the All England Club has now won nine straight matches on grass after having won claimed the title at Eastbourne.
It was Azarenka that prevailed, though, in both the pair's two previous meetings.
The other woman with a shot to head the women's rankings, Agnieszka Radwanska takes to Court One in the remaining last eight matchup against Russian Maria Kirilenko. Incredibly for someone on the verge of becoming world No.1, Radwanska has yet to progress past the quarterfinals of a grand slam in five attempts.
She should feel confident of ending that streak, however, having won five of her seven encounters with 17th seed Kirilenko.