Novak Djokovic
Novak Djokovic's last appearance on Center Court saw him claim his first Wimbledon title with a four-set victory over Rafael Nadal. Reuters

When and where: Day one's play at Wimbledon gets underway at 6.30 a.m. ET. Coverage will be provided by ESPN2, with a live stream available on ESPN3. Viewers in the U.K. can catch the action across the BBC, with a live stream accessible on the BBC Sport website.

Preview: Play begins at this year's championships on the hallowed Centre Court with the traditional appearance of the defending men's champion. An honor that this year falls to world No. 1 Novak Djokovic. Far from the lamb to the slaughter that the title holder regularly goes up against, Djokovic will face a man with oodles of appearance at the top level.

Djokovic certainly wouldn't have been overly pleased to see the name of Juan Carlos Ferrero appear next to his on the draw in the opening round; a stage that is always viewed with a certain apprehension for the big guns in a grand slam.

At 32, Ferrero is certainly past his best, but as a former world No.1 and French Open champion he has pedigree galore. After being seen as very much a clay-court specialist early in his career, the Spaniard has also proved himself on all surfaces, including grass, having twice made the quarterfinals at Wimbledon.

On an impressive day of action on Centre Court, the men's number one seed will immediately be followed by his contemporary in the women's draw, Maria Sharapova.

Having returned to the top of the rankings for the first time since shoulder surgery in 2008, Sharapova is currently riding a huge high. She arrives at SW19 having completed her Career Grand Slam with victory at the French Open and will be favorite to claim her second Wimbledon crown.

And the 2004 champion should have little problem overcoming Anastasia Rodionova, against whom Sharapova has never even lost more than four games in the eight sets played between the pair.

Elsewhere on the women's side, the highlight of the first round draw sees Kim Clijsters face off with former world No. 1 Jelena Jankovic. Clijsters will be playing in her last Wimbledon, with persistent injuries prompting her to announce she will retire after the US open. Despite not having played in three months, the four-time Grand Slam winner showed why she is the most dangerous floater in the draw by reaching the semifinals at the warm-up event in 's-Hertogenbosch before a reoccurrence of an abdominal injury forced her withdrawal.

After a disappointing year, Jankovic reached the final on the grass in Birmingham just over a week ago. But the 18th seed will have to improve upon a 7-1 losing record to Clijsters.

Plenty of fans will also be packed in Court Two to witness five-time champion Venus Williams taking on Elena Vesnina. As she continues to battle the autoimmune disease Sjogren's syndrome, Williams will be desperate for a good run on her favorite surface.

Back to the men's draw and six-time champion Roger Federer begins his quest to equal Pete Sampras' record haul of Wimbledon titles against All-England-Club-debutant Albert Ramos.

There will also be plenty of eyes on Court One as David Nalbandian, fresh from his controversial kick at Queens, faces a tough test versus eighth seed Janko Tipsarevic.