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A woman walks outside British pharmaceutical company AstraZeneca in Macclesfield, northwest England on May 8, 2014. ANDREW YATES/AFP/Getty Images

In a deal designed to build up its cancer drug portfolio, British pharmaceutical giant AstraZeneca announced Thursday that will acquire a 55 percent stake in biotech firm Acerta Pharma for $4 billion. In a statement, the drugmaker said that it may also exercise its option to buy the remaining 45 percent for up to $3 billion.

AstraZeneca said it would pay an initial $2.5 billion for the stake and then a further $1.5 billion upon receipt of the first U.S. regulatory approval for Acerta’s blood cancer drug, Acalabrutinib, or at the end of 2018, whichever comes first.

The transaction will be complete by the end of the first quarter of 2016, pending regulatory approval.

“We are excited to announce this strategic transaction with AstraZeneca, which is a testament to the value inherent in Acerta and Acalabrutinib,” Acerta CEO David Johnson said, in the statement. “AstraZeneca brings tremendous expertise and resources that will help us maximize the potential of Acalabrutinib … we believe we will further accelerate our global clinical development program and maximize the future commercial potential of Acalabrutinib.”

The drug, which has shown promise against an incurable form of leukemia and auto-immune diseases such as lupus, has the potential to become a multi-billion dollar a year seller. It is currently in the most advanced phase of clinical trials.

The ownership of the drug would provide AstraZeneca the arsenal to compete with Johnson & Johnson and AbbVie’s Imbruvica, which was first approved by U.S. regulators in 2013. Both drugs belong to a class known as Burton’s tyrosine kinase inhibitors, which target an array of blood cancers by inhibiting the proliferation of malignant cells.

On Thursday, AstraZeneca's shares were up 2 percent in early trade in London.