While opening for the rock band the Strokes and other bands in New York City on Wednesday, Chris Rock spoke out against the unvaccinated, calling out Brooklyn Nets point guard Kyrie Irving in particular.

"Where’s my anti-vaxxers at? Where you at?" the comedian and "Madagascar" star asked the audience, as reported by Yahoo! Entertainment. Rock continued by saying, “You [expletive] dumb Kyrie [expletive].”

A video of Rock's appearance has since been released by TMZ.

This isn't the first time Rock has spoken out about the COVID vaccine. In September, after testing positive for the virus, he tweeted, "Hey guys I just found out I have COVID, trust me you don't want this. Get vaccinated."

Irving has been the subject of various headlines as he has refused to get the COVID-19 vaccine, and as of October, is not permitted to play with the Nets as a result due to New York City’s COVID-19 vaccine mandate.

“This is about my life and what I’m choosing to do,” Irving said in an Instagram Live on Oct. 13. “And I am being grouped into something that is bigger than just the game of basketball...Nobody is hijacking this voice."