Novak Djokovic
Novak Djokovic continues his quest to win his fourth consecutive grand slam as he plays his second round match at the French Open on Wednesday. Reuters

When and where: Day one action at the French Open gets underway from Paris at 5 a.m. ET. TV coverage will be provided by ESPN2, with the Tennis Channel taking over the reins at 10 a.m. Live stream of the action will be available via ESPN3 and

Preview: After the shock of Serena Williams' stunning loss to France's own Virginie Razzano, big sister Venus will have to pull out all the stops to ensure she does not follow suit on Wednesday. In what on paper is the tie of the round in either the women's or men's draw, Venus goes up against third seeded Agnieszka Radwanska.

The Pole has been phenomenally consistent this season and won the title just last week in Brussels. Radwanska, 23, also got the better of her second-round opponent when the pair last met in the quarter-finals in Miami earlier this year, on route to claiming the title.

Williams will take some solace from the fact that her defeat back in March was only one of just two that she has suffered in seven meetings with Radwanska.

The woman who has tormented Radwanska throughout the year--inflicting an incredible six defeats--Victoria Azarenka, also plays her second-round match on day four. After coming back from a set and 4-0 deficit in her opening match in Paris, the world No. 1 will be hoping for smoother sailing as she takes on qualifier Dinah Pfizenmaier.

There is also plenty to watch out for in the men's draw on Wednesday. The two likeliest contenders to dethrone Rafael Nadal, Novak Djokovic and Roger Federer will both be in action. Yet neither should be unduly tested up against opponents ranked in the 90s.

Roger Federer takes on Romania's Adrian Unqur second on Chartrier,, with world No. 1 Djokovic going up against Blaz Kavcic to get play underway on Lenglen.

Perhaps the most intriguing men's match of the day, though, features home challenger Gilles Simon against the fairytale of the ATP tour in the past two weeks, Brian Baker.

The American, a former world No. 2 in juniors, has had a career ravaged by five surgeries in four years, but came out of nowhere to reach the final in Nice last week. The 27-year-old then continued his run with victory over Xavier Malisse in the opening round at Roland Garros, but will have his work cut out against the 11th seed in round two.

But, while the partisan French crowd will doubtless be rooting for Simon, there are unlikely to be many neutrals who wouldn't love to see Baker score another upset.