NFL Week 1 Picks Against The Spread 2019: Predictions ATS, Updated Betting Odds For Every Game

Five teams are favored on the road in the opening weekend of the 2019 NFL season. Only one home team is laying double digits. The betting line in five games is less than a field goal.

Below are picks against the spread for every game in Week 1, as well as updated betting odds at Las Vegas and online sportsbooks. Betting lines and trends are courtesy of OddsShark.

Atlanta Falcons (+4) at Minnesota Vikings

An improved offensive line will help a loaded Vikings’ offense have plenty of success against a mediocre Falcons’ defense. Matt Ryan has played poorly in recent matchups with Minnesota, and he could be forced into committing a few turnovers against a defense that has Pro Bowlers all over the field.

Prediction ATS: Minnesota

Los Angeles Rams (-2) at Carolina Panthers

This one could go either way, so taking the points with the home underdog is probably the best play. Carolina was 5-0 at home last season before a shoulder injury derailed Cam Newton’s season. A talented Panthers’ front seven might be able to have some success pressuring Jared Goff since the Rams have two new starters on the offensive line.

Prediction ATS: Carolina

Tennessee Titans (+5.5) at Cleveland Browns

The Browns will be a playoff contender, but Cleveland isn’t as good as the hype might suggest. Odell Beckham Jr. could get off to a slow start after a hip injury prevented him from playing in the preseason. Tennessee can control this game with their rushing attack and pull off the upset.

Prediction ATS: Tennessee

Kansas City Chiefs (-3.5) at Jacksonville Jaguars

Patrick Mahomes had his worst game of the 2018 season when he faced the Jaguars. Jacksonville has surrendered 20 points or fewer in 10 straight home games. The Chiefs could escape with a narrow victory.

Prediction ATS: Jacksonville

Baltimore Ravens (-6.5) at Miami Dolphins

It’s hard to lay nearly seven points on the road, even if the home team is trying to earn the No.1 pick in the draft. Maybe Ryan Fitzpatrick will produce some of his magic and make this a competitive game. The Dolphins are 6-2 against the spread in their last eight home games.

Prediction ATS: Miami

Buffalo Bills (+2.5) at New York Jets

The Jets are the better team, even if the betting line says otherwise. Sam Darnold will pick up where he left off after a strong December. Josh Allen’s inaccuracy will keep the Bills from winning on the road.

Prediction ATS: New York

Washington Redskins (+10) at Philadelphia Eagles

The Eagles have as much talent as anyone in the NFC. The Redskins might finish the season with the conference’s worst record. Philadelphia won’t have trouble winning by double-digits.

Prediction ATS: Philadelphia

Indianapolis Colts (+6.5) at Los Angeles Chargers

The Colts can still be an average team with Jacoby Brissett at quarterback. The Chargers are missing key players in safety Derwin James, left tackle Russell Okung and running back Melvin Gordon. This one could be decided by a field goal.

Prediction ATS: Indianapolis

Cincinnati Bengals (+9.5) at Seattle Seahawks

Without A.J. Green, the Bengals are going to have a hard time scoring on the road against a defense that just added Jadeveon Clowney. Russell Wilson will find a way to get Seattle into the end zone a few times for a two-score win.

Prediction ATS: Seattle

Detroit Lions (-2.5) at Arizona Cardinals

Who knows what to expect from Kyler Murray and Kliff Kingsbury in their first meaningful NFL game? The Lions aren’t exactly one of the NFC’s better teams, so maybe the Cardinals’ new-look offense will have some success in its first contest. Detroit is 1-8 against the spread in their last nine visits to Arizona.

Prediction ATS: Arizona

New York Giants (+7.5) at Dallas Cowboys

With so many of their best players missing the entire preseason (Ezekiel Elliott, Amari Cooper, Demarcus Lawrence, Tyron Smith), Dallas could get off to a slow start. An improved offensive line will allow the Giants to move the ball fairly well and stay in the game for most of the way.

Prediction ATS: New York

San Francisco 49ers (+1) at Tampa Bay Buccaneers

There isn’t much reason to be confident that the 49ers are two points better than the Bucs on a neutral field. That means there could be some value on Tampa Bay, who does have the potential to have one of the league’s most explosive offenses under Bruce Arians.

Prediction ATS: Tampa Bay

Pittsburgh Steelers (+5.5) at New England Patriots

Tom Brady has never lost to the Steelers at home. New England went undefeated at Gillette Stadium in 2018 and they’ve won 12 of their last 13 home games by a touchdown or more.

Prediction ATS: New England

Houston Texans (+7) at New Orleans Saints

Don’t be surprised if the Texans win outright. Deshaun Watson is a real MVP candidate now that he has a potential Pro Bowl offensive lineman protecting him. The team that has the ball last might get the victory.

Prediction ATS: Houston

Denver Broncos (-1) at Oakland Raiders

The Raiders are a mess, even with Antonio Brown on the field. The Broncos could have one of the NFL’s top defenses with Vic Fangio at head coach. Don’t be afraid to lay the point on the road against the worst franchise in football.

Prediction ATS: Denver