Tom Brady Patriots 2015
Despite suffering their first loss of the season, Tom Brady and the New England Patriots are Week 13's biggest favorites. Getty Images

The New England Patriots (10-1) will continue their march toward an AFC East title and have home-field advantage when they host the Philadelphia Eagles (4-7) at Gillette Stadium in Week 13. The Patriots are looking for a rebound from their first and only loss, while the Eagles will try to hold on to an opportunity to win the downtrodden NFC East, which they trail by a game.

Tom Brady continued an MVP-caliber season when he threw for 280 yards and three touchdowns in the 30-24 overtime loss to Denver last week and didn’t throw an interception for the first time in four weeks. Brady has 28 passing touchdowns and only four picks as he leads the second-highest scoring offense in the NFL (31.5 points). He may get receiver Danny Amendola back but will be forced to play without Julian Edelman (out for a foot injury) and Rob Gronkowski (out for his knee), who has 57 receptions and nine scores on the season.

The Eagles rank No. 23 in scoring defense (24.9 points) but have given up 90 points the last two weeks as their losing streak extended to three games. Philadelphia allowed 951 yards and 10 passing touchdowns over the last two games and now face Brady, who leads all quarterbacks in passing yards (3,600) and touchdowns.

Chip Kelly remains on the hot seat for the Eagles, who are expecting to get Sam Bradford back under center after he’s missed the last nine quarters with a concussion and shoulder injury. Bradford has thrown 11 touchdowns and 10 interceptions on the season but hasn’t thrown a pick since Oct. 25 against Carolina.

The Eagles rank No. 12 in rushing (114.5 yards per game) but haven’t gotten what they expected out of DeMarco Murray, who has just 545 yards and four scores. Murray was stifled for 30 yards on 14 carries a week ago and has 65 yards or less in seven games this year. Ryan Matthews has rushed for just 118 yards less than Murray despite having 80 less carries on the season.

Despite the myriad of struggles, the Eagles are just one game back of the Giants and Washington in the NFC East and will close out the season versus the Redskins and at New York. The Patriots opened the season with 10 straight victories before losing and haven’t lost two games in a row since September 2012.

Start Time: 4:25 p.m.

TV Channel: FOX

Live Stream: NFL Game Pass

Betting Line: New England -9

Over/Under: 48.5 points