The US coronavirus death toll passed 100,000 as the pandemic tightened its grip on South America, which is outpacing Europe and the United States in daily infections.

Brazil has been hammered by the coronavirus, with deaths and infections soaring Brazil has been hammered by the coronavirus, with deaths and infections soaring Photo: AFP / CARL DE SOUZA

Global cases have surged to nearly 5.7 million, with more than 354,000 deaths, and the worrying acceleration of the disease in South America has marked the continent as the new hotspot.

Deaths in Brazil topped 25,000 on Wednesday, and its caseload is second only to the United States, where authorities have moved to ease lockdowns and help the battered economy, despite experts recommending they remain on guard for a resurgence of the disease.

A government medical worker, in a joint operation with military police, prepares to check passengers on boats in the Melgaco bay, Brazil A government medical worker, in a joint operation with military police, prepares to check passengers on boats in the Melgaco bay, Brazil Photo: AFP / TARSO SARRAF

"Don't start leapfrogging over the recommendations of some of the guidelines because that's really tempting fate and asking for trouble," Anthony Fauci, one of the top US health advisers, told CNN.

A protester sets up bags representing dead bodies during a funeral procession demonstration against the reopening of Florida, in Miami A protester sets up bags representing dead bodies during a funeral procession demonstration against the reopening of Florida, in Miami Photo: AFP / CHANDAN KHANNA

Nearly 1.7 million Americans are known to have been infected with the disease, according to a Johns Hopkins University tally.

Lockdowns in some form will remain necessary until a vaccine or treatment is available, experts have warned, but many governments are under immense pressure to provide relief as businesses and citizens grow weary and resentful of mass confinement.

A medical worker packages a sample from a taxi driver while testing for COVID-19 in Morocco's capital Rabat A medical worker packages a sample from a taxi driver while testing for COVID-19 in Morocco's capital Rabat Photo: AFP / FADEL SENNA

Jair Bolsonaro, Brazil's far-right president and a Trump ally, has slammed stay-at-home orders and played down the threat of the virus, saying the economic fallout of lockdowns causes more damage than the disease itself.

Ballet dancers wearing face masks take part in a rehearsal of Edvard Grieg's Peer Gynt ballet at the Bolshoi Theatre of Belarus in Minsk Ballet dancers wearing face masks take part in a rehearsal of Edvard Grieg's Peer Gynt ballet at the Bolshoi Theatre of Belarus in Minsk Photo: AFP / Sergei GAPON

But infections in Brazil have surged past 411,000, and similar bad news continues to emerge from other South American countries.

Peru logged a record 6,154 new cases in a 24-hour period, with its virus response coordinator Pilar Mazzetti warning that "difficult days, difficult weeks are coming."

Residents get free face masks from a vending machine by scanning their identification card, set up by the government as part of the effort to halt the spread of the COVID-19 in Singapore Residents get free face masks from a vending machine by scanning their identification card, set up by the government as part of the effort to halt the spread of the COVID-19 in Singapore Photo: AFP / ROSLAN RAHMAN

Worried relatives outside the Sabogal Hospital in the capital Lima were unable to enter to see loved ones suffering from COVID-19, with some begging the guards for information.

Doctors protest demanding protection equipment and a wage increase during the lockdown in Buenos Aires Doctors protest demanding protection equipment and a wage increase during the lockdown in Buenos Aires Photo: AFP / JUAN MABROMATA

"I want to talk to a doctor and they don't let me know," said Liset Villanueva, granddaughter of a coronavirus patient.

"They don't say anything, they don't call, they don't explain anything... What is he suffering from?"

A child stands next to bottles and cans as her mother collects water from a tanker in New Delhi as the Indian government eases a nationwide lockdown A child stands next to bottles and cans as her mother collects water from a tanker in New Delhi as the Indian government eases a nationwide lockdown Photo: AFP / SAJJAD HUSSAIN

Worried relatives wait outside a Hospital in Lima, unable to enter, hoping to get some information on their loved ones infected with COVID-19. Worried relatives wait outside a Hospital in Lima, unable to enter, hoping to get some information on their loved ones infected with COVID-19. Photo: AFPTV / Jesus OLARTE

While scientists around the world are racing to develop a vaccine, parallel trials are under way to test treatments for COVID-19 symptoms.

A woman mourns the death of her husband from COVID-19, outside the emergency area at Alberto Sabogal Hospital in Lima A woman mourns the death of her husband from COVID-19, outside the emergency area at Alberto Sabogal Hospital in Lima Photo: AFP / ERNESTO BENAVIDES

France said Wednesday it was banning the anti-malarial drug hydroxychloroquine as a treatment after the World Health Organization suspended its testing over fears of dangerous side effects.

The drug has proved controversial and divisive, with some leaders and governments still backing it -- including President Trump, who said he had taken a course as a preventative measure because he had "heard a lot of good stories" about it.

The United States has now recorded more than 100,000 coronavirus-related deaths -- a somber milestone and by far the highest total in the world The United States has now recorded more than 100,000 coronavirus-related deaths -- a somber milestone and by far the highest total in the world Photo: AFP / Angela Weiss

Health authorities in Brazil and Senegal, and India's top biomedical research body have said they will continue to use it for COVID-19 patients, but the US Food and Drug Administration has warned of serious side effects and poisoning.

The urgency of the coronavirus crisis has prompted some doctors to prescribe the drug despite a lack of research to demonstrate its effectiveness against the new coronavirus.

Didier Roualt, a French infectious disease specialist, insists he has successfully treated dozens of patients with hydroxychloroquine and the antibiotic azithromycin.

He has rejected a comprehensive study in The Lancet medical journal published last week which found that hydroxychloroquine actually increased the risk of death.

As South America and parts of Africa and Asia scramble to deal with their worsening outbreaks, Europe has taken tentative steps to reopen economies and ease lockdowns as new infections slow.

As the continent -- which has lost at least 173,000 people to COVID-19 -- grappled with the human tragedy and economic destruction, the European Union unveiled a 750-billion-euro ($825 billion) recovery plan to get countries back on their feet.

It follows other emergency measures introduced around the world to rescue economies shattered by the virus, which has also shredded the global sports calendar and left fans wondering what events will look like.

While German top-flight football has resumed in empty stadiums, Roland Garros chiefs insisted Wednesday that the French Open will have fans attending even if they still have to abide by social distancing rules when the delayed Grand Slam tournament is held in September.

There was a reminder, however, of the threat still posed by the coronavirus in England, where the globally popular Premier League announced that four more people at its football clubs had tested positive.

Far from the mega-rich sports leagues of the world, millions are simply trying to survive, having lost their livelihoods during the lockdowns.

In South Africa, millions of refugees and migrants mostly depend on day-to-day informal work, which has catastrophically dried up because of strict confinement measures to contain the lockdown.

Now many migrants workers are left with few options, as the government called for locals to be favored for jobs as the economy emerges from the crisis.

"It's very tough, we are starving. Life has become unbearable here."