Two men were arrested for their role in a brawl that occurred in the bathroom at Levi’s Stadium before Sunday’s game between the San Francisco 49ers and the Kansas City Chiefs. Two fans were hospitalized for injuries received in the assault in Santa Clara, California.

The confrontation, which was captured on video, took place shortly before kickoff as fans waited to use a Levi’s Stadium bathroom, Santa Clara police told ABC News in San Francisco. Two men, both wearing 49ers jerseys and hats, assaulted two others, knocking one of them unconscious. They were arrested and charged with felony assault.

"The 49ers are aware of the incident and have been in close contact with Santa Clara police to assist in any way possible on the matter," 49ers spokesman Roger Hackers told ABC.

It’s unclear what prompted the attack, but the video’s uploader wrote on YouTube that the fight occurred after a dispute over an open stall. All four men involved appeared to be 49ers fans. Authorities have yet to reveal their identities or even confirm their team allegiance, but a source said one of the victims suffered a severe head injury. The 49ers won the game, 22-17.

This is the second viral 49ers fan brawl so far this season. On Sept. 22, a group of 49ers fans fought with Arizona Cardinals fans at University of Phoenix stadium in Glendale, Arizona. The fight turned bloody after several brawlers fell down a staircase. At least one person was arrested in connection with the incident.