Oh, Joe. Vice President Joe Biden has a reputation for misspeaking, and his latest verbal blunder -- telling a group of voters that Mitt Romney's tax policy would put "y'all back in chains" -- has bolstered that image. Here's a compilation of Biden's greatest hits -- or, we should say, foul balls.

1. Bright and clean: Biden provoked outrage when he marveled at the fact that then-Senator Barack Obama was "the first mainstream African-American who is articulate and bright and clean and a nice-looking guy." Obama's race was to play a prominent role in the 2008 presidential contest -- from Obama disavowing his former pastor at an African-American church, Jeremiah Wright, to his delivering a stirring speech on the legacy of race in America -- but this initial flareup helped destroy then-candidate Biden's presidential chances.

2. Big f***ing deal: To be fair, President Obama's successfully pushing through a health care overhaul bill, accomplishing a cherished goal that had eluded generations of Democrats, was a big deal. But the signing ceremony for that bill in 2010 is probably not the best time to assure the president that "This is a big f**ing deal," particularly if there is a live mic nearby.

3. Big stick: Biden unleashed a giggle-worthy line earlier this year as he defended Obama's foreign policy against Mitt Romney's charges that the president had been a feckless and timid leader. Invoking President Theodore Roosevelt's mantra of "speak softly and carry a big stick," Biden strayed into innuendo. "I promise you, the president has a big stick," Biden said. "I promise you."

4. Comfortable with same-sex marriage: During an interview on the NBC program "Meet the Press," Biden offered an effusive endorsement of same-sex marriage that far surpassed anything offered by Obama, who had been studiously silent about his own views on the matter. Biden pronounced himself "absolutely comfortable with the fact that men marrying men, women marrying women and heterosexual men marrying women are entitled to the same exact rights," increasing the pressure on Obama to articulate his position. Days later, Obama became the first American president to publicly back same-sex marriage. The administration denied that Biden had forced Obama's hand and the president said he was not upset with Biden, although he acknowledged Biden was "a little bit over his skis" with the comment.

5. A man can't stand up: During a campaign rally, Biden enthusiastically noted that Missouri state senator Chuck Graham was in attendance. "Stand up Chuck, let 'em see you!" Biden said. The only problem: Graham was in a wheelchair, the result of a car accident he was involved in as a teenager.