Just like USC and Georgetown, Purdue has fallen victim to Virginia Commonwealth.
The Boilermakers were the number-three seed in the Southwest Tournament, but lost to the 11th-seed Rams at the United Center, 94-76.
After the new rules that brought a new round to the tournament, VCU becomes the first team to win three games and find themselves in the Sweet 16.
At halftime, VCU was up by 10 points. The Rams continued to their scoring run in the second half with Bradford Burgess leading the way. The guard finished with 25 points and eight rebounds.
The Rams shot an excellent 57.8 percent from the field.
Purdue's JaJuan Johnson, one of the best players in the nation, ended his Boilermaker career with a disappointing loss. The senior forward scored 25 points and added 14 rebounds, to go along with three blocks.
Ryne Smith added 20 points for Purdue in the loss.
The Rams will await the winner of Notre Dame and Florida State.