After 25 years the last episode of Oprah's daytime talk show will air today. Oprah ran for more than 4,500 episodes. The final show was taped yesterday and hosted a number of Oprah's most frequent guests: Jamie Foxx, Stevie Wonder, Jerry Seinfeld, Rosie O'Donnell, Simon Cowell, Maya Angelou, Tyler Perry, Alicia Keys, Aretha Franklin, Usher, Maria Shriver, Tom Cruise, Katie Holmes, Will Smith, Tom Hanks and Kirstin Chenoweth.

Here's a look back on some of Oprah's most memorable moments (and fashion).