Amanda Knox
Amanda Knox, the U.S. student convicted of murdering her British flatmate Meredith Kercher in Italy on November 2007, reacts during her appeal trial session in Perugia, Sept. 23, 2011. Knox walked into a court room in Perugia on Friday for the final stages of an appeal she is hoping will allow her to walk free after nearly four years in an Italian prison. REUTERS/ Reuters

American student Amanda Knox was a naive young woman publicly crucified and impaled to justify wrongly imprisoning her for murder, her lawyer told an Italian court on Thursday.

Knox is appealing a 2009 verdict that found her guilty of murdering her British roommate Meredith Kercher during a drug-fueled sex game that went wrong. Kercher's half-naked body was found in 2007 in a bloody pool in the apartment the two shared.

The Seattle student was sentenced to 26 years behind bars, and prosecutors want the term increased to life.

Her Italian boyfriend at the time, Raffaele Sollecito, and an Ivorian drifter were also jailed over the murder. But much of the focus in the case has been on Knox, who prosecutors allege led the sexual assault and held the knife that slit Kercher's throat.

Wrapping up the defense case, Knox's lawyer Carlo Dalla Vedova pointed to errors in the police investigation and urged a panel of lay and professional judges to look beyond the image of a sex-crazed wild girl created by the media and prosecutors.

She was crucified, impaled in a public square, Dalla Vedova told the court. Who, if not her, has been run over by a media tsunami?

Being respectful of the pain caused by Kercher's death did not mean wrongly jailing two innocent youths, he argued.

She was a girl who was quite different from how she has been depicted, he told the court. How many times have we heard Amanda Knox saying 'Why don't they believe me?'

VERDICT DAYS AWAY

The 24-year-old study abroad student, wearing a silver-gray top on Thursday, has visibly lost weight since her last trial and has appeared frail in her latest appearances in court.

A verdict in the trial is expected by Monday, with the Knox family optimistic their daughter will walk free from an Italian prison that has been her home for nearly four years.

Their hopes have been boosted by a forensics review that cast doubt on traces of DNA found on a kitchen knife and Kercher's bra clasp -- evidence that was used to convict Knox -- and attacked police for sloppy handling of crime scene material.

But prosecutors have since tried to wrest back momentum in the case by focusing on other evidence pointing to Knox and targeting her personality, painting her as a man-eater who resented her roommate and enjoyed flirting with danger.

They allege Knox and Sollecito staged a theft in the Perugia apartment to throw police off track and have attacked Knox's credibility by pointing to her false accusation blaming a Congolese barman for the murder.

Knox says she wrongly accused the barman because she broke down under stressful police questioning. In one particularly sharp attack earlier in the trial, the lawyer for the barman called Knox Satanic, diabolic, a witch and a she-devil.

Defense lawyers have hit back, saying such extreme characterizations are part of a campaign by the prosecution and media to justify a lack of motive in the case by creating a false image of Knox.

Many supporters in the United States see Knox as an innocent student abroad, trapped by an unfair justice system. Her family regularly appear on U.S. talk shows and she is backed by a dogged Internet campaign.

The trial is expected to wrap up by Saturday or Monday at the latest, with Knox expected to address the jury before they decide her fate.