Latest reports out of the New York Jets camp indicate that wide receiver Santonio Holmes will be out for the remainder of the season due to a Lisfranc injury in his left foot.

Holmes suffered the injury during the Jets’ 34-0 loss against the San Francisco 49ers on Sunday when he went down on the first play of the fourth quarter after catching a short pass and fumbling the ball as he fell. The 49ers cornerback Carlos Rogers returned the dropped ball 51 yards for a touchdown.

While Holmes exited MetLife Stadium on a golf cart, holding crutches and his foot in a boot, subsequent MRI exam results were sent to a foot specialist in North Carolina for further evaluation.

“Obviously, it looks doubtful for this week,” Coach Rex Ryan said Monday, “but further than that, I’m not sure.”

While it wasn’t immediately known if the 28-year-old wide receiver’s foot is fractured, a Lisfranc injury usually involves the tearing of the ligament that holds the first two toes in the foot together. The Jets added earlier Tuesday night that the team would have no further update on Holmes

Recovery time for a Lisfranc injury depends on whether there is a dislocation or fracture, and whether surgery — including screws inserted — is needed.

NFL players to suffer from similar include Oakland wide receiver Jacoby Ford who is out for the year. Houston quarterback Matt Schaub and Raiders running back Darren McFadden have returned to the playing field after missing time last season with Lisfranc injuries.

Holmes has 20 receptions for 272 yards and one touchdown this season. The injury is another wound to the 2-2 Jets roster, which now includes injured key players on both sides of the ball. Earlier in the season, the Jets lost All-Pro cornerback Darrelle Revis to a torn ACL in his left knee.

Meanwhile, still active players aren’t getting any better press as quarterback Mark Sanchez is under much criticism from the media for his shoddy play in recent weeks.

The lack of performance has called many to wonder if Tim Tebow should be the Jets go-to QB in next week’s Monday night matchup against the undefeated Houston Texans.

With Holmes crossed of the list, the Jets receiving corps now consists of Jeremy Kerley, rookie Stephen Hill, Chaz Schilens and veteran Clyde Gates.