But Seattle may have lost more than just a game in Week 12.
Starting cornerbacks Richard Sherman and Brandon Browner are reportedly facing four-game suspensions for violating the NFL's performance-enhancing drug policy.
Sherman and Browner are both appealing the suspensions. Seattle released a statement on Sunday that they are aware of the allegations.
Sherman posted on Twitter: "This is issue will be resolved soon and the truth will come out. Not worried."
The potential loss of Sherman and Browner could have serious implications on the Seahawks' postseason hopes. Pete Carroll's squad has a 6-5 record, and are in contention for a wild-card spot in the NFC, but have relied heavily on their defense backs.
The Seahawks boast one of the best defenses in the NFC. Sherman leads Seattle with four interceptions. Browner, who went to the Pro Bowl in 2011, has three interceptions.