(Reuters) - U.S. Labor Secretary Hilda Solis, a long-time member of President Barack Obama's Cabinet and the first Latina to head a major federal agency, announced plans to resign on Wednesday.
Obama issued a statement lauding Solis for being a "tireless champion for working families".
"I wish her all the best in her future endeavors," he said.
At the same time, a White House official said three Cabinet members planned to remain as Obama begins his second term. They are Health and Human Services Secretary Kathleen Sebelius, Attorney General Eric Holder and Veteran Affairs Secretary Eric Shinseki.