Mexico's Attorney General Arely Gomez Gonzalez (2nd right) looks into the entrance of a tunnel connected to the Altiplano Federal Penitentiary and used by drug lord Joaquin 'El Chapo' Guzman to escape, in Almoloya de Juarez, on the outskirts of Mexico City, July 12, 2015. Reuters

A manhunt was underway for Joaquin "El Chapo" Guzman, Mexico's most notorious drug lord, who escaped from a high-security federal prison where he had been housed since last year. At least one expert said he fears unless Guzman is caught in the next 48 hours, he will never be found.

Authorities are now looking for Guzman, who is best known for having led Mexico's powerful Sinaloa Cartel, and have set up numerous check points in hopes of finding the criminal who escaped. Numerous reports say authorities have ordered a massive manhunt. Additionally, Mexican Federal Police are patrolling roads near Altiplano, the maximum security federal prison from which Guzman escaped, in hope of finding the fugitive.

There also have been conflicting reports regarding Toluca airport, which is nearby. The Associated Press said flights had been suspended, but Miguel Perez, the airport's director, told Vice News he had received no instructions to cancel flights. Besides a slight increase in security, the airport was operating as normal, Perez said.

Further South at the Mexico-Guatemala border, Guatemala has set up a special task force consisting of police and soldiers who are patrolling for any sign of the fugitive. Guatemala's Ministry of the Interior, meanwhile, has said Guatemala is keeping in constant communications with the Mexican embassy to coordinate their efforts to recapture Guzman.

Guzman has fled to Guatemala in the past and was arrested there in 1993. He remained in prison until his original escape in 2001. He was recaptured in February 2014 and taken to Altiplano where he remained until Saturday, reportedly through several miles of tunnels. Reuters reported Sunday Mexican President Enrique Pena Nieto said he has faith authorities will be able to recapture the fugitive.

U.S. Attorney General Lorretta Lynch offered U.S. help in the manhunt, noting Guzman faces numerous U.S. drug trafficking and organized crime charges as well.