Todd Gurley injured his knee against the Philadelphia Eagles. Harry How/Getty Images

The Los Angeles Rams (12-3) on Sunday will look to clinch the No. 2 seed in the NFC when they host the San Francisco 49ers (4-11) at the Los Angeles Memorial Coliseum. A victory in Week 17 ensures the Rams will have a first-round bye.

A Rams loss and a Chicago Bears (11-4) win over the Minnesota Vikings would mean the Rams get the No. 3 seed. There is a 10.1 percent chance of that happening, according to NBC Sports. The Rams are listed as 10-point favorites, while the Vikings are favored by 4.5 points.

Head coach Sean McVay has stated that the Rams will not rest their starters in the season finale as they did in the final week of 2017.

A number of players are dealing with injuries. According to McVay, both running back Todd Gurley and safety LaMarcus Joyner are listed as "day-to-day."

Gurley entered Week 16 as a "game-time decision" due to soreness in his left knee. Though Gurley went through a pregame workout, he was held out of Sunday's 31-9 win over the Arizona Cardinals. The 24-year-old appeared to be in good physical condition during the workout, suggesting that he was held out and limited in practice for precautionary reasons.

There is a decent chance he will play against the 49ers and McVay stated that he is "not concerned" about Gurley's injury.

Joyner suffered an ankle injury against the Cardinals. McVay said Joyner's ankle "checked out pretty clean."

The Rams have had their share of injuries this season. Wide receiver Cooper Kupp was lost for the season with a torn ACL, while veteran cornerback Aqib Talib missed several weeks with an ankle injury.

In Week 16, the Rams had several inactive players: cornerback Darious Williams, guard Jamil Demby, linebackers Ogbonnia Okoronkwo and Trevon Young, as well as defensive tackles Sebastian Joseph-Day and Tanzel Smart were all sidelined.