Matt Ryan Atlanta Falcons
Matt Ryan #2 of the Atlanta Falcons throws a third-quarter pass against the Dallas Cowboys at Mercedes-Benz Stadium on November 18, 2018 in Atlanta, Georgia. Scott Cunningham/Getty Images

The favorites will be asked to cover some big betting lines in Week 12. Three teams are laying more than 10 points, and three others are favored by at least a touchdown. There are four home underdogs on the upcoming schedule.

Below are picks against the spread for every game in Week 12 of the 2018 NFL season, as well as updated betting odds at Las Vegas and online sportsbooks. Betting lines and trends are courtesy of OddsShark.

Chicago Bears (-3) at Detroit Lions

The Bears are in a tough spot, having to play a Thursday afternoon game on the road after hosting “Sunday Night Football.” Chicago could have the much worse quarterback now that Mitchell Trubisky might miss the game with a shoulder injury. Matthew Stafford is used to playing at 12:30 p.m. EDT on Thanksgiving. He’s got 15 touchdown passes and three interceptions on the holiday since 2012, and the veteran might lead Detroit to an upset in the week’s first contest.

Prediction ATS: Detroit

Washington Redskins (+7) at Dallas Cowboys

Colt McCoy is a capable backup quarterback, and he can at least keep Washington competitive. Dallas doesn’t have the kind of offense that blows teams out, and only one of their victories has come by more than a touchdown. Don’t expect to see a ton of points in a game between two top-five scoring defenses.

Prediction ATS: Washington

Atlanta Falcons (+13) at New Orleans

You can’t lay nearly two touchdowns in a divisional game against a team that can score points like Atlanta. Maybe New Orleans will win another blow out after outscoring their previous two opponents by a combined 78 points, but this could be a close shootout like the matchup these two rivals had in Week 3.

Prediction ATS: Atlanta

Cleveland Browns (+3) at Cincinnati Bengals

Cleveland’s offense appears to be vastly improved without Hue Jackson and Todd Haley. Cincinnati’s offense, on the other hand, has been a shell of itself without A.J. Green and Tyler Eifert. The Bengals are dead last in total defense, giving Baker Mayfield and the Browns a real chance to win on the road.

Prediction ATS: Cleveland

Seattle Seahawks (+3.5) at Carolina Panthers

The Seahawks and Panthers might be close to even on a neutral field. Seattle is the smart pick with the point spread north of a field goal. The Seahawks have been in all of their road games until the final minutes. Russell Wilson is playing great football, having posted an average passer rating of 123.2 in his last six games.

Prediction ATS: Seattle

Jacksonville Jaguars (-3) at Buffalo Bills

You can’t bet on the Jaguars as road favorites, especially when they are facing a good defense. Jacksonville has been held to 18 points or fewer five times during their six-game losing streak. The Bills beat the Jets in their only game against a team that currently has a losing record, and they’ve got a chance to steal this one now that Nathan Peterman is off the team.

Prediction ATS: Buffalo

Oakland Raiders (+10.5) at Baltimore Ravens

The Raiders are 0-6 against teams that are .500 or better, losing by an average of 16 points per game. They’ve been defeated by 14 points or more in six of their eight losses. Baltimore is very much in the AFC wild-card race, and they should have no trouble with Oakland at home, where the Ravens have outscored opponents by 52 points in five games. The Raiders have covered the spread in just three of their last 12 road games.

Prediction ATS: Baltimore

San Francisco 49ers (+3.5) at Tampa Bay Buccaneers

Tampa Bay has been a disaster since getting off to a 2-0 start, winning no games in regulation over their last eight contests. Both Jameis Winston and Ryan Fitzpatrick are turnover machines, making it difficult to take the Bucs as more than a three-point favorite against anyone.

Prediction ATS: San Francisco

New York Giants (+6) at Philadelphia Eagles

Whether it’s because of a Super Bowl hangover or not, the Eagles are a bad team at the moment. The Giants are finally utilizing their superstar offensive weapons. Odell Beckham Jr. could have a big afternoon against a decimated secondary that’s been awful in the last few weeks. Philadelphia is 1-4 against the spread in their last five home games.

Prediction ATS: New York

New England Patriots (-9.5) at New York Jets

The Jets haven’t proven they can hang with good teams. New York lost to Minnesota and Chicago by 20 points and 14 points, respectively, in consecutive weeks in their only contests against opponents that are above .500. The Patriots are 16-6 against the spread in their last 22 road games.

Prediction ATS: New England

Tom Brady New England Patriots
Tom Brady #12 of the New England Patriots throws a pass against the Tennessee Titans during the first quarter at Nissan Stadium on November 11, 2018 in Nashville, Tennessee. Silas Walker/Getty Images

Arizona Cardinals (+12) at Los Angeles Chargers

The Chargers don’t have a home-field advantage, and it becomes more evident each week. Los Angeles is 2-2 in their own building. They lost to Denver last week and barely beat San Francisco earlier this season. Arizona’s defense is good enough to keep this game within single digits.

Prediction ATS: Arizona

Miami Dolphins (+8) at Indianapolis Colts

Indianapolis is rolling with four straight wins. Andrew Luck hasn’t been sacked in five straight games, and he should have plenty of time to put up more big numbers against a defense that can’t rush the quarterback. Having Ryan Tannehill under center instead of Brock Osweiler will help Miami, but not enough to keep this game close.

Prediction ATS: Indianapolis

Pittsburgh Steelers (-3) at Denver Broncos

Just about every opponent has trouble playing in Denver. The Chiefs and Rams beat the Broncos by a combined seven points. The Broncos would have beaten the Texans in their last home game if Vance Joseph didn’t cost Denver with his poor clock management. Sunday’s game could look a lot like Pittsburgh’s visit to Jacksonville, which the Steelers probably should have lost.

Prediction ATS: Denver

Green Bay Packers (+3) at Minnesota Vikings

Minnesota is the better overall team. Green Bay can’t win on the road, going 0-5 away from Lambeau Field. As long as Kirk Cousins can hold onto the ball, the Vikings should win and eliminate the Packers from playoff contention.

Prediction ATS: Minnesota

Tennessee Titans (+6) at Houston Texans

The Titans have already beaten the Texans once with Blaine Gabbert under center this season. Tennessee is well-coached, and it’s hard to blow them out if you don’t have an explosive offense. Houston has scored 23 points or fewer five times during their seven-game winning streak.

Prediction ATS: Tennessee

Season Record: 73-82-6