Half of the road teams are favored in Week 2. Underdogs covered more spreads than favorites in the opening week of the 2019 NFL season, a trend that could continue Sunday.

Below are picks against the spread for every game in Week 2, as well as updated betting odds at Las Vegas and online sportsbooks. Betting lines and trends are courtesy of OddsShark.

Tampa Bay Buccaneers (+7) at Carolina Panthers

The line is pretty high, but it’s hard to take Jameis Winston on the road against a good team. Expect Cam Newton to look much more comfortable in his second regular-season game back from shoulder surgery. Home favorites are usually a good bet on “Thursday Night Football.”

Prediction ATS: Carolina

Minnesota Vikings (+3) at Green Bay Packers

Week 1 didn’t provide any optimism that Green Bay’s offense will be better with Matt LaFleur replacing Mike McCarthy. The Vikings will keep this one close, at the very least, behind an elite defense that has consistently been able to limit Aaron Rodgers’ effectiveness under Mike Zimmer.

Prediction ATS: Minnesota

Jacksonville Jaguars (+8.5) at Houston Texans

The addition of Laremy Tunsil didn’t prevent Deshaun Watson from getting pummeled on several occasions in Week 1. Jacksonville’s defensive line can make the quarterback uncomfortable and keep the Jaguars competitive on the road.

Prediction ATS: Jacksonville  

Indianapolis Colts (+3) at Tennessee Titans

The Colts have won 13 of their last 15 matchups with Tennessee, going 12-3 against the spread. The Titans beat the Browns by picking off Baker Mayfield three times last week. Jacoby Brissett has a historically low interception rate.

Prediction ATS: Indianapolis 

Jacoby Brissett Indianapolis Colts Jacoby Brissett of the Indianapolis Colts looks to pass in the second quarter of a game against the Arizona Cardinals at Lucas Oil Stadium on Sept. 17, 2017 in Indianapolis. Photo: Getty Images

Arizona Cardinals (+13.5) at Baltimore Ravens

Lamar Jackson won’t have a second straight perfect passer rating. This should be a low-scoring game, making the two-touchdown underdog your best bet against the spread.

Prediction ATS: Arizona

San Francisco 49ers (+2) at Cincinnati Bengals

Let’s see what Jimmy Garoppolo can do on the road when the opposing quarterback doesn’t throw three interceptions. Even when they finished in last place a year ago, the Bengals went .500 at home.

Prediction ATS: Cincinnati 

Los Angeles Chargers (-2.5) at Detroit Lions

The Lions might have a pretty good defense this season in their second year under Matt Patricia. Detroit has a chance to pull off the home upset against the Chargers, who are still missing key players after narrowly defeating the Colts in L.A.

Prediction ATS: Detroit

New England Patriots (-19) at Miami Dolphins

It’s never a good idea to lay 19 points on the road, even against a Dolphins’ team that’s this bad. The Patriots have a habit of underperforming in Miami. The Dolphins could easily cover the spread with some garbage-time scoring. 

Prediction ATS: Miami

Buffalo Bills (-1.5) at New York Giants

The Bills weren’t nearly impressive enough in Week 1 to be favored against a team with which they shared the same preseason projected win total. Josh Allen won’t have the same success against the Giants’ defense that Dak Prescott did.

Prediction ATS: New York 

Seattle Seahawks (+4) at Pittsburgh Steelers

Look for the Steelers to have a big-time bounce-back performance. Ben Roethlisberger could pick apart one of the NFL’s worst secondaries after Andy Dalton threw for 418 yards in Seattle.

Prediction ATS: Pittsburgh

Dallas Cowboys (-4.5) at Washington Redskins

Dallas has all the tools to be a legitimate Super Bowl contender. Case Keenum could struggle against a good defense. There’s little reason to be optimistic about a Redskins’ defense that just gave up 25 second-half points. The Cowboys are 5-1 in their last six road games in Washington. The Redskins are 3-6 against the spread in their last nine matchups with Dallas.

Prediction ATS: Dallas

Kansas City Chiefs (-7.5) at Oakland Raiders

Kansas City’s defense is so bad that it allowed Gardner Minshew to have a historic debut when the rookie suddenly had to take over as Jacksonville’s quarterback. Oakland’s offensive line appears to be much better than anticipated. The Chiefs should win a high-scoring game that could easily be decided by a touchdown or less.

Prediction ATS: Oakland

Derek Carr Oakland Raiders Quarterback Derek Carr #4 of the Oakland Raiders celebrates a win against the San Francisco 49ers late in the fourth quarter on December 7, 2014 at O.co Coliseum in Oakland, California. Photo: Brian Bahr/Getty Images

New Orleans Saints (+2.5) at Los Angeles Rams

This is the best game on the Week 2 schedule. Neither team has a decided edge over the other, making the home Rams the right pick with the point spread at less than a field goal. Los Angeles did find a way to win in New Orleans a few months ago in the NFC Championship Game.

Prediction ATS: Los Angeles 

Chicago Bears (-2.5) at Denver Broncos

Mitchell Trubisky hasn’t proven that he should be a road favorite in Denver. It’s a virtual guarantee that the Broncos will get more pressure on the quarterback than they did in the season opener. Denver hasn’t lost at home in the first two weeks of the season since 2011.

Prediction ATS: Denver 

Philadelphia Eagles (-1.5) at Atlanta Falcons

The Eagles might be the best team in the NFC. Philadelphia is 4-1 against the spread in their last five road games. Atlanta’s defense isn’t to be trusted against a team like the Eagles that can beat you in so many different ways.

Prediction ATS: Philadelphia

Cleveland Browns (-2.5) at New York Jets

It’s still a risky proposition to take the Browns as road favorites. The Jets thoroughly outplayed the Bills for three and a half quarters. Sam Darnold could look much better in Week 2.

Prediction ATS: New York