Serena Williams' retirement is imminent. The tennis star said in a story for Vogue that she is "evolving away from the sport," and all indications are that the 2022 U.S. Open will be the final tournament of her career.

Williams is a 23-time grand slam champion and arguably the greatest female athlete of all time. What are the chances that Williams will go out on top by winning this year's U.S. Open?

Williams' odds to win her final grand slam tournament suggest that she has a legitimate chance to become the U.S. Open champion, though she isn't among the favorites. Williams has +1600 odds for the U.S. Open at BetMGM. The 40-year-old is tied with Bianca Andreescu for the 10th-best odds in the field.

Iga Swiatek, the No. 1 player in the WTA rankings, is favored with +200 odds to win the U.S. Open. Two-time U.S. Open champion Naomi Osaka is second with +500 odds. No other player has better than +1000 U.S. Open odds.

A six-time U.S. Open champion, Williams was forced to withdraw from the tournament last year in the first round because of a torn hamstring. The injury sidelined Williams for 10 months until she made her return at June's Rothesay International tournament in Eastbourne, England.

In the first round of Wimbledon 2022, Williams was defeated by Harmony Tan. Williams' last won a grand slam title at the 2017 Australian Open.

"The countdown has begun," Williams said in an Instagram post. "I have to focus on being a mom, my spiritual goals and finally discovering a different, but just exciting Serena. I'm gonna relish these next few weeks."

It hasn't been that long since Williams threatened to win her 24th Grand Slam. Williams reached the semifinals of the 2020 U.S. Open and the 2021 Australian Open. Williams was the runner-up at Wimbledon and the U.S. Open in both 2018 and 2019.

In order to win the 2022 U.S. Open, Williams would have to shatter her own record. She became the oldest grand slam champion in the Open Era at 35 years old when she won the 2017 Australian Open.

In 2015, Williams' streak of three straight U.S. Open titles was snapped when Flavia Pennetta became the tournament's oldest winner at 33 years old.

Serena Williams of the U.S. serves to Ana Ivanovic of Serbia during their women's singles match at the Australian Open 2014 tennis tournament in Melbourne