The top aftermarket NYSE Losers Wednesday were: Guggenheim Strategic Opportunities, Covance, Varian Medical Systems, LIN TV, NRG Energy, Quantum Corp, Denbury Resources, EQT Corp, InterOil Corp and Petroquest Energy Inc.

Guggenheim Strategic Opportunities Fund (NYSE:GOF) shares plunged 5.14 percent to $21.03 in aftermarket trading session. GOF announced Wednesday that it has commenced a public offering of 1,500,000 common shares pursuant to the Fund’s effective shelf registration statement filed with the U.S. Securities and Exchange Commission (the SEC).

Covance Inc. (NYSE:CVD) shares plunged 4.6 percent to $44.98 in aftermarket trading session. Its fourth quarter net income declined to $21.14 million or $0.35 per share from $28.38 million or $0.45 per share in the same period a year-earlier.

For the first fiscal 2012, the company expects earnings to be in a range of $2.50 to $2.80 per share while analysts’ expect the company to report earnings per share of $2.94.

Varian Medical Systems, Inc. (NYSE:VAR) shares declined 4.32 percent to $66.25 in post market trading session. The company reported first quarter net profit of $90.2 million or $0.79 per share compared to $96.5 million or $0.80 per share in the same quarter last year and against analysts’ estimation of $0.75 per share.

LIN TV Corp. (NYSE:TVL) shares declined 4.18 percent to $3.90 in aftermarket trading session. The stock has a 52-week low of $1.75, a 52-week high of $6.56 and $229.86 million in market capitalization.

NRG Energy, Inc. (NYSE:NRG) shares declined 3.95 percent to $16.64 in aftermarket trading session. The company stock surged more than 5 percent in regular trading session.

Quantum Corp. (NYSE:QTM) shares declined 3.91 percent to $2.70 in aftermarket trading session. The company reported third quarter net income of $3.9 million or $0.02 per share compared to $5.9 million or $0.03 per share in the same quarter a year-ago.

Denbury Resources, Inc. (NYSE:DNR) shares declined 3.03 percent to $18.52 in aftermarket trading session. The stock has a 52-week low of $10.20, a 52-week high of $26.03 and $7.48 billion in market capitalization.

EQT Corp. (NYSE:EQT) shares declined 2.86 percent to $49.50 in aftermarket trading session.

InterOil Corp. (NYSE:IOC) shares declined 2.77 percent to $67.00 in aftermarket trading session. The stock has a 52-week low of $31.18, a 52-week high of $81.92 and $3.31 billion in market capitalization.

Petroquest Energy Inc. (NYSE:PQ) shares declined 2.75 percent to $6.5 in aftermarket trading session.