Juan Martin del Potro celebrates his win over Rafael Nadal. Julian Finney/Getty Images

After a contentious women's final at Flushing Meadows on Saturday, the men take the court on Sunday when two-time U.S. Open champion Novak Djokovic faces 2009 U.S. Open champion Juan Martin del Potro in the final.

No. 3 Del Potro enters as the underdog, but has looked very sharp in the tournament. In the semifinal, the Argentine won two sets against defending champion Rafael Nadal, before Nadal retired due to knee pain. No. 6 Djokovic reached the final by defeating Kei Nishikori in straight sets.

Both players have battled through their share of injuries in recent years.

Del Potro admitted that he got depressed because of injuries to his wrists and even contemplated retirement.

"I was close to quitting this sport because I couldn't find a way to fix my wrist problems," the 29-year-old said. "I have been suffering a lot. I got depressed for a couple of months.

"I didn't expect to get these kind of emotions playing tennis again. Reaching the finals, winning titles, having my highest ranking ever in this moment — everything is almost perfect."

Djokovic, who didn't compete in last year's U.S. Open, has battled back from elbow problems. The Serbian star appears to be back on track after winning Wimbledon in July.

"There was always part of me that believed I could come back relatively quickly to the level of tennis that I once was playing," Djokovic said after his win over Nishikori. "But at the same time, I felt like the six months off served me very well to find new motivation, inspiration, to recharge my batteries."

Djokovic leads the head-to-head matchup, 14-4, which includes two wins in their two U.S. Open meetings. Djokovic and del Potro have not met in a Grand Slam since the 2013 Wimbledon semifinal, which Djokovic won in five sets.

Oddsmakers list Djokovic as the 4/9 favorite, while del Potro has 7/4 odds.

Start Time: 4 p.m. ET

TV Channel: ESPN