British actor Bob Hoskins is retiring from his craft after being diagnosed with Parkinson's disease.

Hoskins, 69, whose most well-known and acclaimed roles include "Who Framed Roger Rabbit," "Mrs. Henderson Presents" and "Mona Lisa," made the announcement in a statement Wednesday.

"Bob Hoskins wishes to announce that he will be retiring from acting, following his diagnosis of Parkinson's disease last autumn," the statement read, according to Sky News. "He wishes to thank all the great and brilliant people he has worked with over the years, and all of his fans who have supported him during a wonderful career. Bob is now looking forward to his retirement with his family, and would greatly appreciate that his privacy be respected at this time."

Parkinson's disease affects movement in sufferers and is caused by nerve cells that break down and no longer produce dopamine, according to WebMD.

Onset of the disease usually starts in later in life, between the ages of 50 and 60, although 1 in 20 affected by Parkinson's disease are in their 20s through 40s.

The most common symptoms of Parkinson's disease include tremor, stiff muscles, slow movement and problems with balance or walking, according to WebMD. There is no cure for the disease.

Hoskins first introduced himself to film audiences with a cameo appearance in the 1972 British comedy "Up The Front."

He went on to have a successful career making movies. Hoskins received a best actor Oscar nomination in 1987 for "Mona Lisa," where he plays an ex-con driving around a prostitute. The actor won a Golden Globe for that role.

Other accolades for Hoskins included Golden Globe nominations for "Who Framed Roger Rabbit" in the best actor category and a Golden Globe best supporting actor nod for "Mrs. Henderson Presents."

The 69-year-old actor is not the only high-profile thespian dealing with Parkinson's disease.

Actor Michael J. Fox was diagnosed with an early onset form of the disease in 1991 when he was just 30 years old. Fox has since become a leading advocate for research on a cure for Parkinson's as well as lobbying for stem cell research.