The surgeons of Grey Sloan Memorial Hospital were divided on Thursday night during episode 21 of “Grey’s Anatomy.” In the Season 12 installment of the hit ABC series, Callie and Arizona went head to head as they began their extremely messy custody battle, which meant splitting up their friend group.

In order to win guardianship of little Sofia (Eva Ariel Binder), both Callie (Sara Ramirez) and Arizona (Jessica Capshaw) need to have a friend to speak on their behalf in court to prove they’re the better parent. And trying to find a buddy willing to take sides during Battle Calzona turned to be out harder than either of them expected.

“Today is the day I lose all my friends,” Callie says, warning Penny (Samantha Sloyan) that attempting to rally supporters is going to be taxing mission — especially since most of them are also friends with her ex.

“Are you asking me to take the stand for the custody thing?” Alex (Justin Chambers) questions after Callie asks if he’ll take her side. “The answers no. I like you both.”

But Callie isn’t the only one having trouble finding someone who will take her side during court. Initially Arizona thinks April (Sarah Drew) and Jackson Avery (Jesse Williams) will have her back — that is, until she takes an ultrasound of April’s stomach. During the ultrasound April notices a change in Arizona’s face and demands an explanation.

“It’s the baby’s brain,” Arizona reluctantly tells the expecting couple who previously lost a child do brittle bone disease.

“You said that everything was fine weeks ago,” April says in a panic, questioning Arizona that maybe she didn’t look thoroughly enough during the first ultra sound. April then asks Arizona to leave the room with tears rolling down her cheeks — a scene Penny witnesses after being placed on her service.

Arizona has let the pressure of this custody battle get to her and has an emotional break down in her car. That’s when Weber (James Pickens Jr.) hops into the passenger seat to give his friend a much-needed pep talk.

“If you want your daughter you’re going to have to fight like you never fought,” he tells her. “Do you want to lie down? You don’t get to.”

So, with a fire lit under her, Arizona claws and fights her way back to the person, mother and doctor she knows she can be. And her first mission of proving just how capable she can be is by finding out if there’s something wrong with April’s baby. After putting April under to get a closer look at her baby, Arizona is able to conclude that there is “definitively nothing” wrong with the Avery baby.

But Arizona tells the couple that this would be the last time she’d ever be giving April an ultrasound.

“I can’t be your doctor,” Arizona tells then. “If I’m your doctor I can’t be your friend. And I want to be your friend.”

Sounds like Arizona may have just found someone to take the stand for her in court! While Arizona has the Avery couple in her corner, Meredith (Ellen Pompeo) and Owen (Kevin McKidd) both agree to bolster Callie in court.

Other Major Moments From Episode 21

Stephanie Breaks Up With Kyle

Stephanie (Jerrika Hinton) ends her relationship with Kyle (Wilmer Valderrama) after she realizes that she can’t be the person who waits for a loved one in a waiting room.

In episode 21 Kyle is forced to undergo surgery once again after a new tumor forms in his brain. But due to Stephanie’s personal relationship with the musician, Amelia (Caterina Scoresone) forbids her resident for partaking in the case.

Steph tells Jo (Camilla Luddington) that she broke up with Kyle because she can’t be sidelined during a surgery. She needs to be in the operating room instead of on the “other side of the red line.”

“I choose me,” she tells Jo.

Amelia and Owen Take Their Relationship to the Next Level

After years of being on-again-off-again couple, Amelia and Owen finally decided to make their romance official (thanks to a little nudge from Mer).

“I know that I make this tough. It feels like work because it’s going to be work,” she tells Owen. “If you and I decided to be together — like really together — I might wind up screwing all of this up.”

“So let’s screw things up,” Owen replies.

“Grey’s Anatomy” airs Thursdays at 8 p.m. EDT on ABC.