Comedy Central’s taking viewers to the South Side of Chicago with the premiere of its new series tonight, appropriately titled “South Side.”

Co-created by former “Late Night with Jimmy Fallon” writers Bashir Salahuddin and Diallo Riddle, the new scripted comedy follows two friends and recent community college graduates, Simon James (played by Bashir’s brother, Sultan Salahuddin) and Kareem “K” Odom (Kareme Young), who are ready to do big things.

Until that happens, though, “they’re stuck at Rent-T-Own, a retail-rental crossroads where the South Side's vast ensemble of characters come together,” according to the synopsis. “Despite the obstacles of inner-city life, these friends and their co-workers all strive to achieve their entrepreneurial dreams.”

south side cast comedy
Sultan Salahuddin as Simon James and Kareme Young as Kareem "K" Odom in Comedy Central’s “South Side.” Comedy Central

The “South Side” cast also features Chandra Russell (“Downtown Girls”) as Sergeant Turner, Bashir as Officer Goodnight, Riddle as Allen Gayle and Kareme’s twin brother Quincy Young as Quincy Odom.

Comedy Central fans will also see various guest stars in the 10-episode first season, including Lil Rel Howery, Nathaniel “Earthquake” Stroman, Jeff Tweedy, LisaRaye McCoy, Kel Mitchell and Ed Lover.

Head to Chicago when “South Side” premieres on Comedy Central on Wednesday at 10:30 p.m. EDT.

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