Japanese retail company Uniqlo will open its biggest location in the world on Friday. The store, located on Fifth Avenue, will mark the company's second in the U.S. (Photo: http://www.uniqlo.com)

Japanese clothing company Uniqlo is gearing up to open its biggest retail location in the world: on New York City's Fifth Avenue.

Located at 666 Fifth Avenue, the former Brooks Brothers space of 89,000 square feet will feature 100 dressing rooms and 50 cash registers, according to CNN.

While Friday's opening will mark Uniqlo's second store in the U.S., the company is quickly following up with an Oct. 21 opening of a store on New York's historic 34th Street, along with several pop-up shops around the city.

Uniqlo's first U.S. store, located in SoHo, has been in operation since 2006.

Famous for its affordable colorful cashmere sweaters, jeans and Heattech wear, Uniqlo has remained a strong player in the retail market, despite the country's current 9.1 percent unemployment rate.

We're really excited . . . we have a great store on the best shopping street in New York, Uniqlo U.S. CEO Shin Odake told CNN.

In recent weeks, Uniqlo has been hyping up its New York store openings with an advertising campaign called Voices of New York. Famous New Yorkers like Susan Sarandon, John Leguizamo, Laura Linney, Darren Criss (Glee) and others can be seen in poster form and on the store's Web site, sharing their personal New York stories while sporting Uniqlo attire.

This is not the first time the company has dipped into Hollywood. In August 2010, Uniqlo named Orlando Bloom and Charlize Theron as the company's brand ambassadors.

With one day to go, buzz of Uniqlo's newest store has also been bursting at the seams of Twitter.

Be still your beating heart: Uniqlo's 5th Ave flagship store's grand opening is tomorrow! Don't miss our opening day deals & free totes! the company wrote on Thursday.

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To celebrate the Fifth Avenue opening on Friday, Uniqlo will sell denim for a discounted price of $9.90. The sale ends on Oct. 30.

Like many of its locations around the world, Uniqlo Fifth Avenue will feature walls lined with sweaters arranged by color, jeans and other items.

New York Mayor Michael Bloomberg is expected to cut the ribbon at Friday's opening, Fader first reported.

Uniqlo Fifth Avenue joins an already busy shopping strip, with Gap, Zara, H&M, Hollister and Swatch nearby.

Uniqlo has more than 790 locations in Japan, with 99 in Tokyo alone. Around the world, the company's store count is just over 1,000.

Fast Retailing, Uniqlo's owner, already has plans to open 200 to 300 stores a year worldwide, including locations in major U.S. cities like Los Angeles and Chicago, according to the Financial Times.