Twitter was flooded again Saturday with loads of tweets related to yet another celebrity death hoax, and this time the target is pop queen Madonna.

According to many Twitter users, RIP Madonna emerged because the singer's latest single, Give Me All Your Luvin, has turned into a flop, despite its launch amid huge hype.

Madonna performed on the song at the U.S. Super Bowl earlier this month, and it was reportedly watched by a record American TV audience of 114 million, plus millions more globally.

RIP Madonna her body had so much plastic surgery that she is like a perfectly preserved mummy now, a Twitter user posted.

Adele beats Madge's record for the longest chart reign by a female solo artist and RIP Madonna trends. How cruel!, posted another Twitter user.

Oh, come on with the RIP Madonna TT. You guys, Madonna is not dead. That's just her career, said another user.

Some of Madonna fans blamed Lady Gaga's fans for circulating the death hoax over the social networking site.

Some Gaga's fans are so stupid and immature. RIP Madonna? Call me when Gaga is the best selling female living legend of all time, read a tweet.

RIP Madonna?! -__-' well, how do Ü guys feel it if another fanbase trend something like RIP Gaga??!!? #StopVirtualHate!!!!! another tweet read.

Many of the pop diva's fans obviously looked angry and disappointed.

RIP Madonna NO. Were loosing everybody and you thinks it's funny to say that? Seriously!? You all are probably hobos on computers, a Twitter user said.

RIP Madonna? Seriously STOP! Thats not okay at all. Its not funny, its not classy, its not right. We just lost Whitney, death is NOT a joke, read another tweet.

There is a big difference between RIP and R.I.P.! RIP Madonna = Really Inspiring Person, another user posted.

Her latest single Give Me All Your Luvin, the first of her new album, MDNA, looks likely to drop out of the top 40 completely this weekend, just a week after entering the British charts at 37. According to latest figures, it could come down to 51 by Sunday if current sales levels continue, the Daily Mail reported.