U.S. Congressman Anthony Weiner speaks to the media in New York
U.S. Congressman Anthony Weiner (D-NY) speaks to the media in New York, June 6, 2011. Representative Anthony Weiner admitted on Monday to sending a lewd photo of himself to a 21-year-old female college student over his Twitter account after previously denying he had done so. REUTERS/Brendan McDermid

Congressional Republicans eager to capitalize on Congressman Anthony Weiner's salacious Twitter scandal are calling for his head.

House Majority Leader Eric Cantor told congressional reporters Rep. Weiner's revelations are a distraction from the important work congress must conduct.

We've got a lot of serious challenges going on in this country and a lot of work for Congress to do, Cantor said. The last thing we need is to be immersed in discussion about Congressman Weiner and his Twitter activities.

I certainly don't condone his activity and I think he should resign, the GOP big quipped.

Cantor's condemnation came hours after House Democratic Leader Nancy Pelosi formally requested an Ethic Committee probe into Weiner's actions.

Weiner's admitted his conduct was inappropriate, Pelosi in a letter to committee Chairman Jo Bonner (R-AL) and Linda Sanchez (D-CA) formally requesting an inquiry by the committee.

An investigation by the Ethics Committee to determine whether the Rules of the House of Representatives have been violated is warranted, Pelosi said in the letter.

The congressman who's 9th district covers Brooklyn and Queens admitted Monday to sending sexually explicit photographs of himself to about a half dozen women as well as engaging in explicit exchanges with them over text message and social media.

Senate Majority Leader Harry Reid sought to distance himself from Weiner's conduct when he spoke to reporters Tuesday.

I know Congressman Weiner. I wish there was some way I could defend him, but I can't, Reid said.

Reid said if Weiner is looking for help call somebody else.