Jeb Bush
Former Florida Gov. Jeb Bush delivers remarks at the Conservative Political Action Conference in National Harbor, Maryland, in this file photograph taken March 15, 2013. Reuters

Nearly a quarter-century after choosing between a Bush and a Clinton at the polls, Americans could be presented with the same options in 2016, according to the most recent betting odds. Post-midterm numbers indicate that Hillary Clinton is most likely to be the Democratic candidate for president, while Jeb Bush could take the Republican nomination eight years after his brother left office.

Clinton - - the former first lady, U.S. senator and secretary of state - - is currently the clear favorite to win the presidency in 2016 with 5/4 odds from, a popular sports gambling site. Jeb Bush, the former Florida governor, comes in second place with 8/1 odds. Neither politician has officially announced a run, but if Bush were elected, he would take office 28 years after his father and only eight years after his older brother bowed out.

Other possible candidates who were rated include Marco Rubio (11/1 odds), Rand Paul (12/1), Chris Christie (12/1), Elizabeth Warren (14/1) and Mitt Romney (25/1). This is in no small part because Clinton is universally seen as the inevitable candidate. Along with her already extensive resume, she nearly beat President Barack Obama for the Democratic nomination in 2008 and is far more popular than Vice President Joe Biden (33/1).

Like Clinton, Bush has been reluctant to discuss whether he’ll run in two years. When he does speak, though, he usually mentions what U.S. leaders need to do to make sure the American people are successful. Along with being a proven winner in a swing state, Bush gained points by campaigning for Republicans in the just-completed 2014 midterm elections.

“Americans could always count on hard work leading to higher incomes and improved lives,” he wrote in a October fundraising letter, as quoted by “The American dream was real and within reach. But today, among the developed nations, we are the least economically and socially mobile country in the world.”