The New Orleans Saints and Philadelphia Eagles are both underdogs Sunday despite being two of the conference’s top Super Bowl contenders. The Los Angeles Rams and Kansas City Chiefs aren’t the heavy favorites they were projected to be after losses in Week 5.

There’s no such thing as a “sure thing” when it comes to gambling, but here are the five best bets against the spread for Week 6 of the 2019 NFL season. These are the betting odds from the Westgate Las Vegas Super Contest.

New Orleans Saints (+1.5)

The Saints have a strong case to be considered the best team in the NFC. Even though they are underdogs, the back-to-back NFC South champs should be expected to win Sunday’s road game against the Jacksonville Jaguars.

New Orleans has three wins against teams that are above .500, winning with both defense and offense. Teddy Bridgewater finally put up big numbers last week when Sean Payton let him air it out, throwing for four touchdowns and over 300 yards. Jacksonville’s defense isn’t what it once was, failing to rank better than 19th in points allowed, yards allowed and opponents’ yards per play. The Jaguars are 0-3 against teams that own winning records.

Philadelphia Eagles (+3)

Kirk Cousins and the Minnesota Vikings continue to beat up on bad teams and lose to playoff contenders. Until they prove otherwise, it’s hard to expect Minnesota to defeat the NFC East’s best team.

The Eagles’ offense is starting to fire on all cylinders with the team scoring more than 30 points in two straight games. The unit moved the ball at will two weeks ago against a Packers’ defense that’s been among the league’s best. If this is a close game, Carson Wentz will make the big plays down the stretch that Cousins can’t. Dalvin Cook could have his worst game of the season against Philadelphia’s No.1 ranked run defense.

Carson Wentz Philadelphia Eagles
Quarterback Carson Wentz #11 of the Philadelphia Eagles celebrates a touchdown by teammate tight end Zach Ertz #86 against the Dallas Cowboys during the fourth quarter at Lincoln Financial Field on November 11, 2018 in Philadelphia, Pennsylvania. Elsa/Getty Images

Kansas City Chiefs (-4.5)

One loss doesn’t mean the Chiefs are no longer among the AFC’s elite teams. Kansas City should bounce back at home with a win over the Houston Texans.

The opening betting line for Sunday’s contest at Arrowhead Stadium was 8.5 points, according to OddsShark, before the Chiefs lost to the Colts in Week 5. A few dropped passes and Patrick Mahomes tweaking his ankle twice cost Kansas City against Indianapolis. This is still an offense that scored more than 25 points in 23 straight games with Mahomes under center. Houston gave up 30 points the only time they faced a top-15 scoring offense this season.

Los Angeles Rams (-3)

The San Francisco 49ers still have to beat a good team before they can be declared the best team in the NFC West. Look for them to suffer their first loss of 2019 when they visit the Rams.

Los Angeles is in a prime position to bounce back after two straight losses. It’s been two years since the Rams scored fewer than 23 points at home with Jared Goff as the starting quarterback. Despite not playing their best football, L.A. is still sixth in points per game. The 49ers could be in trouble if their defense doesn’t dominate the way it has over the team’s first four games.

Detroit Lions (+4)

Detroit is one of the NFL’s most underrated teams and a real threat to win the NFC North. They can cover the spread, at the very least, in their road game against the Green Bay Packers. The Lions might even win outright on “Monday Night Football.”

The Lions are a last-minute Patrick Mahomes touchdown drive away from still being undefeated in Week 6. Detroit has impressive wins against the Chargers and Eagles. The defense that made Mahomes look human and held Philip Rivers to a 73.0 passer rating can limit Aaron Rodgers’ effectiveness. Green Bay’s quarterback has failed to reach the 240-yard mark in four of five games. The Lions are 4-1 against the spread in their last five meetings with Green Bay.

Season Record: 9-14-2