The first COVID-19 vaccine in the U.S. was given on Monday morning to a New York State ICU Nurse.

Sandra Lindsay was the first to receive the vaccination, but she’s the first of many that’ll be receiving the poke throughout the day and the week.

"It didn't feel any different from taking any other vaccine," Lindsay said after the shot was administered.

Watch her receive the shot in New York Gov. Andrew Cuomo's live stream below:

After MSNBC took to Twitter to inform the world of the historic moment, thousands of users shared their thoughts.

Lindsay is a critical care nurse who’s been working with COVID-19 patients for months. She works at the Long Island Jewish Medical Center located in Queens, New York.

"I hope this marks the beginning to the end of a very painful time in our history. I want to instill public confidence that the vaccine is safe. We're in a pandemic and we all need to do our part to put an end to the pandemic," Lindsay said, adding that she trusts science.

Both Lindsay and Cuomo emphasized that Americans have to "do their part" and get the vaccine, wear masks, and social distance.

More than 20 million doses of the vaccine could be administered to Americans before the end of 2020, U.S. officials say.

The vaccine was approved by the Food and Drug Administration on Friday, and it’s said to be 95% effective.

Front-line healthcare workers, along with long-term care facility residents will be the first of Americans in line to receive the shot, an FDA Advisor told NPR.

Gen. Gustave Perna, who’s the chief operating officer of Operation Warp Speed, explained in a press briefing on Saturday more about what’s anticipated during this first week of distribution.

“We expect 145 sites across all the states to receive the vaccine on Monday, another 425 sites on Tuesday, and the final 66 sites on Wednesday, which will complete the initial delivery of the Pfizer orders,” Perna stated.

Sandra Lindsay
Sandra Lindsay(L), a nurse at Long Island Jewish Medical Center, is inoculated with the Covid-19 vaccine by Dr. Michelle Chester, at Long Island Jewish Medical Center, on December 14, 2020 in the Queens borough of New York. MARK LENNIHAN/POOL/AFP via Getty Images