The New England Patriots are one of the biggest favorites in recent memory when they host the New York Jets in Week 3 of the 2019 NFL season. There’s good reason to believe the defending Super Bowl champions will easily cover the large point spread.

The betting line for Sunday afternoon’s game is up to 22.5 points, according to OddsShark. The over/under is 43.5.

Sam Darnold is still out with mononucleosis. Backup quarterback Trevor Siemian was lost for the season Monday night with an ankle injury. That means third-string signal caller Luke Falk will be under center when the Jets inevitably lose at Gillette Stadium.

Falk did complete 20 of 25 passes when he relieved Siemian in Week 2. It didn’t help New York much, however, as the team fell to the Cleveland Browns 23-3 at home.

The Patriots have been more dominant than anyone to start the season, outscoring the Pittsburgh Steelers and Miami Dolphins by 73 points. New England looks like an even better team than the one that hoisted the Vince Lombardi Trophy in February for the sixth time. 

The defense still hasn’t surrendered a touchdown, allowing three total points in its last three games dating back to Super Bowl LIII. It won’t be all that surprising if Falk and the Jets can’t break that streak.

New York will need to get healthier on defense if they want to have a prayer of slowing down Tom Brady and Co. Baker Mayfield threw for 325 yards in Week 2 when linebacker C.J. Mosley and defensive end Quinnen Williams were sidelined with injuries.

Antonio Brown led the Patriots with four catches for 56 yards in New England’s 43-0 win in Miami. Assuming Brown will still be allowed to play despite his off-the-field issues, the Patriots have three No.1-caliber receivers on the roster. 

Odell Beckham Jr. had six catches for 161 yards against the Jets in Week 2. John Brown caught seven passes for 123 yards against New York in the season opener. 

Tom Brady Patriots Jets Tom Brady #12 of the New England Patriots in action against the New York Jets during their game at MetLife Stadium on November 25, 2018 in East Rutherford, New Jersey. Photo: Al Bello/Getty Images

The Jets haven’t been competitive at Gillette Stadium over their last few visits. New York was blown out in Foxboro 38-3 last year when Darnold was healthy. That was preceded by a 26-6 defeat in New England in 2017 and a 41-3 loss in 2016. 

Why would things get any better with Luke Falk at quarterback against maybe the best Patriots’ team since New England went 16-0 more than a decade ago?

The Jets have failed to cover the spread in their last five games, according to OddsShark. The Patriots are 6-0 against the spread in their last six games.

Bill Belichick has shown no mercy to his opponents in two consecutive one-sided victories to start the season. Brady continued to throw the ball late in the fourth quarter in both contests when New England was up by more than 30 points. 

Sunday should be more of the same for the NFL’s best team.

Prediction: New England over New York, 37-10