New England Patriots
The New England Patriots are 4-0, winning each game by an average of more than 18 points. Getty

Some of the NFL’s best teams are on the road in Week 6, making half of the home teams on the schedule underdogs. That also means a lot of small betting lines, including 10 of four points or less.

Even though the New England Patriots are visiting the first-place Indianapolis Colts, they are the second-biggest favorites of Week 6. Facing the Colts for the first time since last year’s AFC Championship Game, where the Deflategate scandal began, New England is giving Indianapolis more than a touchdown. Andrew Luck is back at practice, but it’s unknown if he’ll miss a third straight game. The over/under of 55 points is the highest of Week 6.

The Green Bay Packers are the only undefeated team that’s home in Week 6, and they are the biggest favorites on the schedule, giving 9.5 points to the San Diego Chargers. Aaron Rodgers and Co. are perfect against the spread, winning every game by at least eight points.

Coming off a bye week, the Carolina Panthers are the only undefeated team that is an underdog in Week 6. They are getting seven points in their visit to Seattle. The Seahawks are 2-3, having blown a 17-point, fourth quarter lead against the Cincinnati Bengals last week. Carolina visited Seattle in last year’s playoffs, losing by 14 points.

The Houston Texans are the smallest favorites of the week, giving one point to the Jaguars in their visit to Jacksonville. Houston’s one victory came against Tampa Bay, who beat Jacksonville in Week 6.

The Giants are in sole possession of first place in the NFC East, but the point spread in their visit to Philadelphia indicates that they wouldn’t be favored against the Eagles on a neutral field. It’s Philadelphia’s second appearance on “Monday Night Football” in 2015.

The Dallas Cowboys, Oakland Raiders, St. Louis Rams and Tampa Bay Buccaneers have a bye in Week 6.

Below are the complete betting lines for all the Week 6 games, including the point spreads and totals. These are the consensus odds from multiple sportsbooks in Las Vegas, via

Atlanta Falcons (-3.5) at New Orleans Saints, 51

Denver Broncos (-4) at Cleveland Browns, 42

Cincinnati Bengals (-2.5) at Buffalo Bills, 44.5

Kansas City Chiefs (+3.5) at Minnesota Vikings, 44

Houston Texans (-1) at Jacksonville Jaguars, 43

Chicago Bears (+3) at Detroit Lions, 43

Washington Redskins (+5.5) at New York Jets, 40.5

Arizona Cardinals (-4) at Pittsburgh Steelers, 45.5

Miami Dolphins (+2.5) at Tennessee Titans, 43.5

Carolina Panthers (+7) at Seattle Seahawks, 41

San Diego Chargers (+9.5) at Green Bay Packers, 51

Baltimore Ravens (-2.5) at San Francisco 49ers, 44

New England Patriots (-7.5) at Indianapolis Colts, 55

New York Giants (+3.5) at Philadelphia Eagles, 50.5