• Reps for ABC confirmed that Ingo Rademacher ended his association with "General Hospital" last week
  • Actress Nancy Lee Grahn also said that Rademacher was "mercifully" no longer a part of the cast
  • Rademacher was a series regular on the long-running medical drama for 25 years

"General Hospital" star Ingo Rademacher is out at the long-running ABC soap opera after he refused to comply with the production's COVID-19 vaccine mandate, multiple outlets have confirmed.

Representatives for ABC confirmed to The Hollywood Reporter that Rademacher ended his association with "General Hospital" prior to Sunday, when the 50-year-old actor posted a transphobic meme and anti-vax sentiment on social media.

Rademacher has played the character Jasper "Jax" Jacks on the daytime medical drama since 1996 and has been a regular on the show for 25 of its 59 seasons.

Rademacher will still appear in "General Hospital" in the next few weeks, and his last episode is scheduled to air on Nov. 22.

The "Titans" star has been vocal about his anti-vaccination beliefs. On Sunday, he shared on Instagram calls for a walkout by health care and government workers who do not agree with the vaccine mandate.

"I will stand with you to fight for medical freedom," Rademacher wrote in the caption, adding hashtags for "medical freedom," "no mandates," "woke," "awakening" and "coercion is not consent."

Rademacher received support from several of his fans and fellow celebrities. Sonya Balmores commented with a raising hands emoji, while his "General Hospital" co-star Derk Cheetwood commented, "I stand for medical freedom as well!"

News of Rademacher's exit from "General Hospital" also came just a day after he received intense backlash for sharing an anti-trans tweet on Instagram that misgendered Rachel Levine, who is transgender and was recently sworn in as an admiral of the U.S. Public Health Service Commissioned Corps, as a "dude" and mocked the notion that Levine could be considered an empowered woman.

His co-star Cassandra James, a transgender woman, called him out on Twitter over his post, and he apologized to her. Several other members of the cast, including Nancy Lee Grahn, Laura Wright and Wes Ramsey, also supported James.

In her response to James' tweet, Grahn confirmed that Rademacher was no longer part of the "General Hospital" cast.

"The fellow actor, #IngoRademacher, is mercifully no longer a part of the #gh cast," she wrote. "Transphobia & misgendering are disgusting & should be unacceptable in any industry, including soaps/acting. I stand with my costar, @cassandrajames_, & the trans community."

Meanwhile, Rademacher addressed the transphobic meme in a new video he posted on Instagram Monday. He stood by the message of the tweet but said he should have crossed out the word "dude" from the original post, adding that he doesn't think "it's OK to call a transgender an empowered woman because where does that leave women?"

"I do apologize for not crossing out 'dude' and putting 'transgender,'" he said. 

General Hospital Pictured: Ingo Rademacher as Jasper “Jax” Jacks on the ABC soap opera “General Hospital.” Photo: ABC/Nick Agro