A drive-by shooting early Wednesday at a school bus stop in Louisville, Kentucky, has left a 16-year-old boy dead and two other teens injured. 

A teenage boy was taken to a hospital for non-life-threatening injuries, while a 14-year-old girl was treated for minor injuries at the scene. The shooting happened at 6:30 a.m. ET.

There is no suspect in custody. The Louisville Metro Police Department put out a statement requesting for anyone with information to call their department. 

Louisville police released a photo on social media of a dark gray Jeep SUV with Illinois license tags with the plate number BD91644.

"A school bus stop," said Mayor Greg Fischer at a press conference. "Which should be a sacred space in our community, a safe space where there should be every expectation of safety and security."

All three students attend the Eastern High School, Jefferson County Public Schools (JCPS), according to  Superintendent Marty Pollio.

“This is one of our toughest days at JCPS. We have suffered another devastating loss to senseless gun violence. Our hearts go out to the family of the Eastern HS student whose life was ended. We are providing support for the students,” Pollio tweeted.

Louisville has had 145 homicides in 2021, according to Fischer.