AHS Hotel Premiere
Detective John Lowe (Wes Bentley) checks into "American Horror Story: Hotel" when it premieres on FX Wednesday, Oct. 7 at 10 p.m. ET. FX

Think you’re ready to check in at Hotel Cortez? “American Horror Story” fans are about to find out! Season 5, “Hotel,” premieres on Wednesday, Oct. 7. But before viewers unpack their bags and settle in, take a few moments to meet the new cast of characters.

As previously reported, episode 1 of “Hotel” will introduce viewers to the mysterious Hotel Cortez. It is believed that the Los Angeles building is linked to a “chain of gruesome murders” in town. While the hotel is undoubtedly full of dark secrets … the residents are just as suspicious.

Angela Bassett as Ramona Royale

AHS Ramona
Angela Bassett is Ramona Royale on "American Horror Story: Hotel." FX

Hello, Ramona! Played by returning cast member Angela Bassett, Ramona Royale is a film star who has a romantic history with Lady Gaga’s character Elizabeth. However, Entertainment Weekly reports that the women are now at odds. In fact, Ramona wants revenge on Elizabeth.

Kathy Bates as Iris

Kathy Bates AHS
Kathy Bates is Iris on "American Horror Story: Hotel." FX

In Season 5 Kathy Bates is tackling Iris, the manager of Hotel Cortez. Iris lives at the hotel with her son, Donovan (Matt Bomer). She continuously butts heads with tenant Hypodermic Sally (Sarah Paulson) and works on crossword puzzles.

Wes Bentley as John Lowe

AHS Wes Bentley
Wes Bentley is Detective John Lowe on "American Horror Story: Hotel." FX

Viewers should be worried about John Lowe. Wes Bentley’s character is a detective with the Los Angeles police department investigating a string of murders committed by the “10 Commandments Killer.” TV Guide reveals that Detective Lowe is “lured” to Hotel Cortez by a call from the killer. And unfortunately for Lowe, the killer is interested in his personal life.

Matt Bomer as Donovan

AHS Donovan
Matt Bomer is Donovan on "American Horror Story: Hotel." FX

Beware the wrath of Donovan. Matt Bomer’s character is the son of Iris and a lover to Elizabeth (Lady Gaga). Unfortunately for Donovan, his lady love becomes interested in another man … leading him to seek revenge on her alongside Ramona.

Lady Gaga as Elizabeth

Lady Gaga AHS
Lady Gaga is Countess Elizabeth on "American Horror Story: Hotel." FX

Lady Gaga portrays Elizabeth on “American Horror Story: Hotel.” But Elizabeth also goes by “The Countess.” The character is the owner of Hotel Cortez and suffers from an “ancient blood virus.”

Cheyenne Jackson as Will Drake

Will Drake
Cheyenne Jackson is Will Drake on "American Horror Story: Hotel." FX

Will Drake, played by Cheyenne Jackson, is a single father and New York fashion designer. However, lost creativity and passion draws him to California … and Hotel Cortez. Jackson confirmed to MTV that his character will have a “chaotic” relationship with Elizabeh.

Denis O’Hare as Liz Taylor

Denis O'Hare Liz Taylor
Denis O'Hare is Liz Taylor on "American Horror Story: Hotel." FX

Don’t be fooled, Denis O’Hare is not portraying actress Liz Taylor. But his “American Horror Story” character is a bartender at Hotel Cortez who is obsessed with Taylor.

Sarah Paulson as Hypodermic Sally

AHS Sarah Paulson
Sarah Paulson is Hypodermic Sally on “American Horror Story: Hotel.” FX

Hypodermic Sally is a junkie that lives at Hotel Cortez. Sarah Paulson’s character has a twisted history with Iris and Donovan that will be explored this season in a flashback to 1994.

Evan Peters as Mr. James March

Evan Peters James March
Evan Peters is James March on "American Horror Story: Hotel." FX

Evan Peters’ character, James March, will help tell the story of “Hotel” from a different time period – the 1930s. James March was the original owner and builer of the hotel. Peters revealed to EW that his character “designed a hotel to cater to his specific needs, which tend toward the dark evil.”

Chlöe Sevigny as Alex Lowe

AHS Chlöe Sevigny
Chlöe Sevigny is Alex Lowe on "American Horror Story: Hotel." FX

Alex Lowe, played by Chlöe Sevigny, is a pediatrician and the wife of Detective John Lowe. Both Alex and John are suffering from a major loss when the season starts.

“American Horror Story: Hotel” premieres on FX on Wednesday, Oct. 7 at 10 p.m. ET.