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President Barack Obama said MH17 was shot down by a surface-to-air missile in an area controlled by pro-Russian separatists.
The U.S. ambassador to the U.N. gave the strongest implication yet from the U.S. on Russia's possible role in the MH17 crash.
Russian military defense company Almaz-Antey was targeted in sanctions a day before one of its missiles possibly shot down MH17.
Russia has said it is willing to cooperate in the investigation, but only if the blaming from Ukraine stops.
Russia also claimed that the jetliner was being guided by Ukrainian air-traffic controllers.
Here is a set of facts about Flight MH17, which was a Boeing 777-200 aircraft.
Ukraine is worried investigations into the crash might be compromised if pro-Moscow rebels hand over the box to Russia.
Aviation authorities from several countries have either banned air routes passing through Ukraine or advised carriers against using them.
The Boeing 777 airplane was carrying 298 people on board when it crashed into a village about 25 miles from the Russian border.
The former U.S. Secretary of State also called on the European Union to join the U.S. in taking a tougher stand against Moscow.
The Security Service of Ukraine posted a recording of three allegedly intercepted phone calls between militants and Russian intelligence.
Malaysia Airlines said air traffic controllers lost contact with flight MH-17 as it flew over eastern Ukraine toward the Russian border, bound for Asia.
Missiles launched from the ground or the air have brought down civilian aircraft several times before, intentionally or by mistake.
To allow recovery work to proceed at the site of downed Malaysian Air flight MH17, pro-Russian separatists are willing to have a three-day cease-fire.
The two world leaders had previously arranged to discuss the ongoing Ukraine crisis.
The Malaysia Airlines MH17 plane crash in Ukraine generated hundreds of thousands of comments on Twitter.
As the world searches for an explanation for the crash of MH17, coincidences lead to conspiracy theories.
The Federal Aviation Authority barred U.S. pilots from flying over Crimea, after armed conflict broke out in the Ukrainian region.
Several airlines have announced changes in their flight routes following the crash of Malaysia Airlines Flight MH17 in Ukraine on Thursday.
All 295 people aboard the Boeing 777 flying from Amsterdam to Kuala Lumpur were killed.
A Malaysia Airlines Boeing 777 passenger jet flying from Amsterdam to Kuala Lumpur was shot down in Ukraine, reports news agency Interfax.