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"The Oprah Winfrey Show," which aired for 25 seasons, from 1986 to 2011. The show received a whopping 47 Daytime Emmy Awards before Oprah's 2000 decision to cease submitting it for consideration. Reuters

Born on Jan. 29, 1954, in Kosciusko, Miss., Oprah Winfrey defied all odds to take her place as one of the world’s most powerful media moguls and leaders.

Launching her career as the first black woman to anchor the news at Nashville's local WTVF-TV station, Oprah worked tirelessly at perfecting her craft to ultimately become one of the most recognized faces on televisions around the world. Continually encouraging people to always strive for their best, she has cemented her place in history as the first black female billionaire, a fearless entrepreneur and a friend to viewers worldwide who tuned in to her iconic “Oprah Winfrey Show.”

In celebration of the extraordinary Oprah's 60th birthday today, below we've gathered 25 of Oprah’s best quotes about love, success and the power of positive thinking.

1. “I don’t believe in accidents. I know for sure that everything in life happens to help us live.”

2. “Be thankful for what you have; you'll end up having more. If you concentrate on what you don't have, you will never, ever have enough.”

3. “Surround yourself with only people who are going to lift you higher.”

4. “The greatest discovery of all time is that a person can change his future by merely changing his attitude.”

5. “I believe that every single event in life happens in an opportunity to choose love over fear.”

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In November 2013, U.S. President Barack Obama presented Oprah with the highest civilian honor, the Presidential Medal of Freedom. Reuters

6. “Think like a queen. A queen is not afraid to fail. Failure is another steppingstone to greatness.”

7. “The struggle of my life created empathy - I could relate to pain, being abandoned, having people not love me.”

8. “Follow your instincts. That's where true wisdom manifests itself.”

9. “I don't think you ever stop giving. I really don't. I think it's an on-going process. And it's not just about being able to write a check. It's being able to touch somebody's life.”

10. “I am a woman in process. I'm just trying like everybody else. I try to take every conflict, every experience, and learn from it. Life is never dull.”

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During her talk show's run, Oprah interviewed numerous entertainers, activists, world leaders and everyday people, including well-known figures like former Secretary of State Hillary Clinton. Reuters

11. “Breathe. Let go. And remind yourself that this very moment is the only one you know you have for sure.”

12. “I don't think of myself as a poor deprived ghetto girl who made good. I think of myself as somebody who from an early age knew I was responsible for myself, and I had to make good.”

13. “For everyone of us that succeeds, it's because there's somebody there to show you the way out.”

14. “I still have my feet on the ground, I just wear better shoes.”

15. “Unless you choose to do great things with it, it makes no difference how much you are rewarded, or how much power you have.”

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Oprah was the richest African American of the 20th century, according to Forbes. Reuters

16. “Doing the best at this moment puts you in the best place for the next moment.”

17. “You CAN have it all. You just can't have it all at once.”

18. “The more you praise and celebrate your life, the more there is in life to celebrate.”

19. “I feel that luck is preparation meeting opportunity.”

20. “The whole point of being alive is to evolve into the complete person you were intended to be.”

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Oprah poses with high school students during her school's first graduation ceremony in 2012 at the Oprah Winfrey Leadership Academy for Girls at Henley-on-Klip. The school is located outside Johannesburg. Reuters

21. “So go ahead. Fall down. The world looks different from the ground.”

22. “I don't believe in failure. It is not failure if you enjoyed the process.”

23. “If you want to accomplish the goals of your life, you have to begin with the spirit.”

24. “The thing you fear most has no power. Your fear of it is what has the power. Facing the truth really will set you free.”

25. “It does not matter how you came into the world, what matters is that you are here.”