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Snow covers trees during a winter storm on Feb. 21, 2019 in Las Vegas, Nevada. Winter Storm Scott is expected to affect 95 million people nationwide. Ethan Miller/Getty Images

A winter storm will deliver a combination of heavy snow, rain, and a wintry mix, followed by a blast of record-setting cold temperatures across the United States.

Winter Storm Scott is expected to roar through the interior of the Northeastern part of the U.S. from Sunday to Monday. Areas from the southern Appalachians to the southern parts of New England will also experience anywhere from rain to a wintry mix to heavy snowfall.

Approximately 95 million people in the Northeast alone are projected to be affected by the storm system, with a number of travel delays and school closings already anticipated for Monday.

In addition to heavy precipitation, a blast of cold air will sweep through the Central states into the Southeast and up through the East Coast on Saturday into Sunday, inducing record-setting cold temperatures.

On Sunday morning through the afternoon, snow and a wintry mix will descend upon the central Appalachians, ascending to the coastal Mid-Atlantic region and as far north as New York state's Hudson Valley.

Anywhere from 6 to 12 inches of snow is expected in areas in between the Ohio Valley and northwestern New England, including western and northern Pennsylvania and the middle of New York state.

More mountainous regions are projected to receive up to 16 inches of snowfall.

A mix of rain, sleet, and snow will possibly fall along the I-95 corridor, affecting a major throughway from Washington, D.C., to Baltimore, Philadelphia, New York City and Boston.

Heavy rain will also be possible over parts of the Southeast, most notably the Tennessee Valley, then move on through the coast.

According to the National Weather Service, temperatures in the Northern Plains and Central Plains will range from 20 to 48 below average, with some places in the Plains with a wind chill of nearly 55 degrees below zero.

Montana will get a major brunt of the cold rush, with temperatures predicted to reach 40 degrees below zero minus windchill.

The cold weather will then branch out southward, with near-freezing temperatures as far as Florida early next week.​